Chronic treatment with the AMP-kinase activator AICAR increases glycogen storage and fatty acid oxidation in skeletal muscles but does not reduce hyperglucagonemia and hyperglycemia in insulin deficient rats
长期使用 AMP 激酶激活剂 AICAR 治疗可增加骨骼肌中的糖原储存和脂肪酸氧化,但不能降低胰岛素缺乏大鼠的高血糖素血症和高血糖症。
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0062190
Vitzel, Kaio F; Bikopoulos, George; Hung, Steven; Pistor, Kathryn E; Patterson, Jessica D; Curi, Rui; Ceddia, Rolando B