日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Production of clinical grade patient iPSC-derived 3D retinal organoids containing transplantable photoreceptor cells

制备含有可移植感光细胞的临床级患者来源的iPSC衍生3D视网膜类器官

Bohrer, Laura R; Wiley, Luke A; Wright, Allison T; Hittle, Bradley; Lang, Mallory J; Affatigato, Louisa M; Powell, Kimerly A; Haefeli, Lorena M; Han, Ian C; Mullins, Robert F; Stone, Edwin M; Tucker, Budd A

Conditional Immortalization Using SV40 Large T Antigen and Its Effects on Induced Pluripotent Stem Cell Differentiation Toward Retinal Progenitor Cells.

利用 SV40 大 T 抗原进行条件永生化及其对诱导多能干细胞向视网膜祖细胞分化的影响

Wang Qi, Allen Brittany N, Bohrer Laura R, Burnight Erin R, Tucker Budd A, Worthington Kristan S

Demonstration of the pathogenicity of a common non-exomic mutation in ABCA4 using iPSC-derived retinal organoids and retrospective clinical data.

利用 iPSC 衍生的视网膜类器官和回顾性临床数据,证明 ABCA4 中常见非外显子突变的致病性

Burnight Erin R, Fenner Beau J, Han Ian C, DeLuca Adam P, Whitmore S Scott, Bohrer Laura R, Andorf Jeaneen L, Sohn Elliott H, Mullins Robert F, Tucker Budd A, Stone Edwin M

Automated human induced pluripotent stem cell colony segmentation for use in cell culture automation applications

用于细胞培养自动化应用的自动化人类诱导多能干细胞集落分割

Powell, Kimerly A; Bohrer, Laura R; Stone, Nicholas E; Hittle, Bradley; Anfinson, Kristin R; Luangphakdy, Viviane; Muschler, George; Mullins, Robert F; Stone, Edwin M; Tucker, Budd A

Patient derived stem cells for discovery and validation of novel pathogenic variants in inherited retinal disease

利用患者来源的干细胞发现和验证遗传性视网膜疾病中的新型致病变异

Mullin, Nathaniel K; Voigt, Andrew P; Cooke, Jessica A; Bohrer, Laura R; Burnight, Erin R; Stone, Edwin M; Mullins, Robert F; Tucker, Budd A

CRISPR-Cas9 genome engineering: Treating inherited retinal degeneration

CRISPR-Cas9基因组编辑:治疗遗传性视网膜变性

Burnight, Erin R; Giacalone, Joseph C; Cooke, Jessica A; Thompson, Jessica R; Bohrer, Laura R; Chirco, Kathleen R; Drack, Arlene V; Fingert, John H; Worthington, Kristan S; Wiley, Luke A; Mullins, Robert F; Stone, Edwin M; Tucker, Budd A

p300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis

p300乙酰转移酶调节雄激素受体降解和PTEN缺陷型前列腺肿瘤发生

Zhong, Jian; Ding, Liya; Bohrer, Laura R; Pan, Yunqian; Liu, Ping; Zhang, Jun; Sebo, Thomas J; Karnes, R Jeffrey; Tindall, Donald J; van Deursen, Jan; Huang, Haojie