日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Towards designing improved cancer immunotherapy targets with a peptide-MHC-I presentation model, HLApollo.

利用肽-MHC-I呈递模型HLApollo,设计改进的癌症免疫治疗靶点

Thrift William John, Lounsbury Nicolas W, Broadwell Quade, Heidersbach Amy, Freund Emily, Abdolazimi Yassan, Phung Qui T, Chen Jieming, Capietto Aude-Hélène, Tong Ann-Jay, Rose Christopher M, Blanchette Craig, Lill Jennie R, Haley Benjamin, Delamarre Lélia, Bourgon Richard, Liu Kai, Jhunjhunwala Suchit

Indication-specific tumor evolution and its impact on neoantigen targeting and biomarkers for individualized cancer immunotherapies

针对特定适应症的肿瘤演变及其对新抗原靶向和个体化癌症免疫疗法生物标志物的影响

Lo, Amy A; Wallace, Andrew; Oreper, Daniel; Lounsbury, Nicolas; Havnar, Charles; Pechuan-Jorge, Ximo; Wu, Thomas D; Bourgon, Richard; Jones, Ryan; Krogh, Katrina; Yang, Guang-Yu; Zill, Oliver A

Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation

NF-κB 和 p300/CBP 的激活通过诱导 MHC-I 抗原呈递增强癌症化疗免疫疗法的疗效。

Zhou, Yixuan; Bastian, Ingmar Niels; Long, Mark D; Dow, Michelle; Li, Weihua; Liu, Tao; Ngu, Rachael Katie; Antonucci, Laura; Huang, Jian Yu; Phung, Qui T; Zhao, Xi-He; Banerjee, Sourav; Lin, Xue-Jia; Wang, Hongxia; Dang, Brian; Choi, Sylvia; Karin, Daniel; Su, Hua; Ellisman, Mark H; Jamieson, Christina; Bosenberg, Marcus; Cheng, Zhang; Haybaeck, Johannes; Kenner, Lukas; Fisch, Kathleen M; Bourgon, Richard; Hernandez, Genevive; Lill, Jennie R; Liu, Song; Carter, Hannah; Mellman, Ira; Karin, Michael; Shalapour, Shabnam

Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B

辅助性结直肠癌的转录组分析揭示了三个关键的预后生物学过程以及颗粒酶B在疾病特异性中的作用

Daemen, Anneleen; Udyavar, Akshata R; Sandmann, Thomas; Li, Congfen; Bosch, Linda J W; O'Gorman, William; Li, Yijin; Au-Yeung, Amelia; Takahashi, Chikara; Kabbarah, Omar; Bourgon, Richard; Hegde, Priti; Bais, Carlos; Das Thakur, Meghna

Development of a gene expression-based prognostic signature for IDH wild-type glioblastoma

构建基于基因表达的IDH野生型胶质母细胞瘤预后特征

Johnson, Radia M; Phillips, Heidi S; Bais, Carlos; Brennan, Cameron W; Cloughesy, Timothy F; Daemen, Anneleen; Herrlinger, Ulrich; Jenkins, Robert B; Lai, Albert; Mancao, Christoph; Weller, Michael; Wick, Wolfgang; Bourgon, Richard; Garcia, Josep

Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial

阿特珠单抗作为不适合顺铂治疗的局部晚期和转移性尿路上皮癌患者的一线治疗:一项单臂、多中心、II期试验

Balar, Arjun V; Galsky, Matthew D; Rosenberg, Jonathan E; Powles, Thomas; Petrylak, Daniel P; Bellmunt, Joaquim; Loriot, Yohann; Necchi, Andrea; Hoffman-Censits, Jean; Perez-Gracia, Jose Luis; Dawson, Nancy A; van der Heijden, Michiel S; Dreicer, Robert; Srinivas, Sandy; Retz, Margitta M; Joseph, Richard W; Drakaki, Alexandra; Vaishampayan, Ulka N; Sridhar, Srikala S; Quinn, David I; Durán, Ignacio; Shaffer, David R; Eigl, Bernhard J; Grivas, Petros D; Yu, Evan Y; Li, Shi; Kadel, Edward E 3rd; Boyd, Zachary; Bourgon, Richard; Hegde, Priti S; Mariathasan, Sanjeev; Thåström, AnnChristine; Abidoye, Oyewale O; Fine, Gregg D; Bajorin, Dean F

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial

阿特珠单抗治疗铂类化疗后进展的局部晚期和转移性尿路上皮癌患者:一项单臂、多中心 II 期试验

Rosenberg, Jonathan E; Hoffman-Censits, Jean; Powles, Tom; van der Heijden, Michiel S; Balar, Arjun V; Necchi, Andrea; Dawson, Nancy; O'Donnell, Peter H; Balmanoukian, Ani; Loriot, Yohann; Srinivas, Sandy; Retz, Margitta M; Grivas, Petros; Joseph, Richard W; Galsky, Matthew D; Fleming, Mark T; Petrylak, Daniel P; Perez-Gracia, Jose Luis; Burris, Howard A; Castellano, Daniel; Canil, Christina; Bellmunt, Joaquim; Bajorin, Dean; Nickles, Dorothee; Bourgon, Richard; Frampton, Garrett M; Cui, Na; Mariathasan, Sanjeev; Abidoye, Oyewale; Fine, Gregg D; Dreicer, Robert

Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial

贝伐珠单抗联合一线放疗和替莫唑胺治疗可能使原神经胶质母细胞瘤患者获得总生存获益:AVAglio试验的回顾性分析

Sandmann, Thomas; Bourgon, Richard; Garcia, Josep; Li, Congfen; Cloughesy, Timothy; Chinot, Olivier L; Wick, Wolfgang; Nishikawa, Ryo; Mason, Warren; Henriksson, Roger; Saran, Frank; Lai, Albert; Moore, Nicola; Kharbanda, Samir; Peale, Franklin; Hegde, Priti; Abrey, Lauren E; Phillips, Heidi S; Bais, Carlos

Human biosample authentication using the high-throughput, cost-effective SNPtrace(TM) system

使用高通量、经济高效的 SNPtrace(TM) 系统进行人体生物样本认证

May M Y Liang-Chu, Mamie Yu, Peter M Haverty, Julie Koeman, Janet Ziegle, Marie Lee, Richard Bourgon, Richard M Neve

A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation

突变型 KRas 驱动的信号转导和转化需要野生型 Ras 亚型

Carolyn Bentley, Stefanie S Jurinka, Noelyn M Kljavin, Steffan Vartanian, Sree R Ramani, Lino C Gonzalez, Kebing Yu, Zora Modrusan, Pan Du, Richard Bourgon, Richard M Neve, David Stokoe