日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sequential accumulation of phosphorylated tau species in early Alzheimer's disease

阿尔茨海默病早期磷酸化tau蛋白的顺序积累

Whittington, Robert A; Bretteville, Alexis; Dickler, Maya F; Planel, Emmanuel; Faustin, Arline; Strobbe, Aysha; Balcomb, Kaleah; Kanshin, Evgeny; Kavanagh, Tomas; Genoud, Sian; Pires, Geoffrey; Askenazi, Manor; Ueberheide, Beatrix; Wisniewski, Thomas; Drummond, Eleanor

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes

基因工程改造的iPSC衍生FTDP-17 MAPT神经元表现出突变特异性的神经退行性和神经发育表型

Verheyen, An; Diels, Annick; Reumers, Joke; Van Hoorde, Kirsten; Van den Wyngaert, Ilse; van Outryve d'Ydewalle, Constantin; De Bondt, An; Kuijlaars, Jacobine; De Muynck, Louis; De Hoogt, Ronald; Bretteville, Alexis; Jaensch, Steffen; Buist, Arjan; Cabrera-Socorro, Alfredo; Wray, Selina; Ebneth, Andreas; Roevens, Peter; Royaux, Ines; Peeters, Pieter J

Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domain

Tau蛋白磷酸化调节BIN1的SH3结构域与Tau蛋白富含脯氨酸结构域之间的相互作用。

Sottejeau, Yoann; Bretteville, Alexis; Cantrelle, François-Xavier; Malmanche, Nicolas; Demiaute, Florie; Mendes, Tiago; Delay, Charlotte; Alves Dos Alves, Harmony; Flaig, Amandine; Davies, Peter; Dourlen, Pierre; Dermaut, Bart; Laporte, Jocelyn; Amouyel, Philippe; Lippens, Guy; Chapuis, Julien; Landrieu, Isabelle; Lambert, Jean-Charles

Insulin dysfunction and Tau pathology

胰岛素功能障碍和Tau蛋白病理

El Khoury, Noura B; Gratuze, Maud; Papon, Marie-Amélie; Bretteville, Alexis; Planel, Emmanuel

Deregulation of protein phosphatase 2A and hyperphosphorylation of τ protein following onset of diabetes in NOD mice

NOD小鼠糖尿病发作后,蛋白磷酸酶2A失调和τ蛋白过度磷酸化。

Papon, Marie-Amélie; El Khoury, Noura B; Marcouiller, François; Julien, Carl; Morin, Françoise; Bretteville, Alexis; Petry, Franck R; Gaudreau, Simon; Amrani, Abdelaziz; Mathews, Paul M; Hébert, Sébastien S; Planel, Emmanuel

A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment.

一种转基因大鼠,会出现类似阿尔茨海默病的淀粉样蛋白病理、突触可塑性缺陷和认知障碍

Liu Li, Orozco Ian J, Planel Emmanuel, Wen Yi, Bretteville Alexis, Krishnamurthy Pavan, Wang Lili, Herman Mathieu, Figueroa Helen, Yu W Haung, Arancio Ottavio, Duff Karen

Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

在一种新型突变tau转基因小鼠中,类似阿尔茨海默病的tau蛋白神经病理学导致记忆缺陷和功能性突触丧失,但小鼠没有任何运动缺陷。

Schindowski, Katharina; Bretteville, Alexis; Leroy, Karelle; Bégard, Séverine; Brion, Jean-Pierre; Hamdane, Malika; Buée, Luc