日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enhanced-mRNA Delivery Using Ultrasound-Delivered Anchors for Bioorthogonal Ligation

利用超声递送锚定物增强mRNA递送以进行生物正交连接

Di Ianni, Emilio; Jeon, Jueun; Mohammadi, Sedra; Hu, Huiyu; Quintana, Jeremy M; Lee, Chanseo; Haidar, Edwina Abou; Goemans, Marie; Zargani-Piccardi, Ayrton; Mahamdeh, Mohammed; Hernández, Iván Coto; Rodriguez, Victoria E; Zhou, Yirong; Aguirre, Aaron; Yuan, Shiaulou; Ng, Thomas S C; Breyne, Koen; Lee, Hakho; Breakefield, Xandra O; Miller, Miles A

Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer

胶质母细胞瘤皮质类器官重现细胞状态异质性和细胞间转移

Mangena, Vamsi; Chanoch-Myers, Rony; Sartore, Rafaela; Paulsen, Bruna; Gritsch, Simon; Weisman, Hannah; Hara, Toshiro; Breakefield, Xandra O; Breyne, Koen; Regev, Aviv; Chung, Kwanghun; Arlotta, Paola; Tirosh, Itay; Suvà, Mario L

Engineering of CD63 Enables Selective Extracellular Vesicle Cargo Loading and Enhanced Payload Delivery.

CD63 的工程改造可实现选择性细胞外囊泡货物装载和增强有效载荷递送

Obuchi Wataru, Zargani-Piccardi Ayrton, Leandro Kevin, Rufino-Ramos David, Di Lanni Emilio, Frederick Dawn Madison, Maalouf Katia, Nieland Lisa, Xiao Tianhe, Repiton Pierre, Vaine Christine A, Kleinstiver Benjamin P, Bragg D Cristopher, Lee Hakho, Miller Miles A, Breakefield Xandra O, Breyne Koen

CRISPR targeting of mmu-miR-21a through a single adeno-associated virus vector prolongs survival of glioblastoma-bearing mice

利用单个腺相关病毒载体进行 CRISPR 靶向 mmu-miR-21a 可延长胶质母细胞瘤小鼠的生存期。

Lisa Nieland ,Anne B Vrijmoet ,Isabelle W Jetten ,David Rufino-Ramos ,Alexandra J E M de Reus ,Koen Breyne ,Benjamin P Kleinstiver ,Casey A Maguire ,Marike L D Broekman ,Xandra O Breakefield ,Erik R Abels

Intratumoral delivery of 4-1BBL boosts IL-12-triggered anti-glioma immunity.

肿瘤内注射 4-1BBL 可增强 IL-12 触发的抗胶质瘤免疫力。

Lunavat Taral R, Nieland Lisa, van de Looij Sanne M, de Reus Alexandra J E M, Couturier Charles P, El Farran Chadi A, Miller Tyler E, Lill Julia K, Schübel Maryam, Xiao Tianhe, Di Ianni Emilio, Woods Elliot C, Sun Yi, Rufino-Ramos David, van Solinge Thomas S, Mahjoum Shadi, Grandell Emily, Li Mao, Mangena Vamsi, Dunn Gavin P, Jenkins Russell W, Mempel Thorsten R, Breakefield Xandra O, Breyne Koen

Non-invasive detection of allele-specific CRISPR-SaCas9-KKH disruption of TOR1A DYT1 allele in a xenograft mouse model

在异种移植小鼠模型中,通过非侵入性方法检测 TOR1A DYT1 等位基因的等位基因特异性 CRISPR-SaCas9-KKH 破坏

Katia E Maalouf ,Dawn Madison Frederick ,Nutan Sharma ,Edwina Abou Haidar ,Tianhe Xiao ,Justin Seungkyu Han ,Mohammed S Mahamdeh ,Roy J Soberman ,David Rufino-Ramos ,Benjamin P Kleinstiver ,Hyder A Jinnah ,Christine A Vaine ,D Cristopher Bragg ,Koen Breyne

Arming AAV9 with a Single-Chain Fragment Variable Antibody Against PD-1 for Systemic Glioblastoma Therapy

将针对 PD-1 的单链片段可变抗体植入 AAV9,用于系统性胶质母细胞瘤治疗

Semer Maksoud #, Markus W Schweiger #, Elie I Tabet #, Tianhe Xiao, Joelle El Hokayem, Max Zinter, Litia A Carvalho, Koen Breyne, David P Noske, Ennio Antonio Chiocca, Bakhos A Tannous1

Alternative splicing in the RBMXL1 5'-UTR induces uORF-mediated translation control in activated B lymphocytes.

RBMXL1 5'-UTR 中的选择性剪接诱导活化 B 淋巴细胞中 uORF 介导的翻译控制

de Breyne Sylvain, Polvèche Hélène, Auboeuf Didier, Ohlmann Théophile, Gruffat Henri, Manet Evelyne

Arthroscopic Exposure for Anterosuperior Rotator Cuff Repair

关节镜下前上肩袖修复术

Lebot, Gaspard; Breyne, Lucile; Godenèche, Arnaud

Extracellular vesicles for the delivery of gene therapy

用于基因治疗递送的细胞外囊泡

Di Ianni, Emilio; Obuchi, Wataru; Breyne, Koen; Breakefield, Xandra O