Brian Koss相关文献与解析，生知库 | 链接生命科学的每一步

Jacob L Edmondson ，Megan R Reed ，Daniel Fil ，Billie Heflin ，Alyson McKinnon ，Michael A Bauer ，Lauren C Morehead ，Nathan L Avaritt ，Mary Phillips ，Sean D Taverna ，Alan J Tackett ，Brian Koss

代谢

黑色素瘤

EZH2

发表日期：2025

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Evolved histone tail regulates 53BP1 recruitment at damaged chromatin

进化的组蛋白尾部调节受损染色质处 53BP1 的募集

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-49071-w

Jessica L Kelliher, Melissa L Folkerts, Kaiyuan V Shen, Wan Song, Kyle Tengler, Clara M Stiefel, Seong-Ok Lee, Eloise Dray, Weixing Zhao, Brian Koss, Nicholas R Pannunzio, Justin W Leung

Enhancer-activated RET confers protection against oxidative stress to KMT2A-rearranged acute myeloid leukemia

增强子激活的 RET 为 KMT2A 重排的急性髓系白血病提供针对氧化应激的保护

期刊:Cancer Science

影响因子:4.5

doi:10.1111/cas.16069

Brendan Frett, Kimberly E Stephens, Brian Koss, Stepan Melnyk, Jason Farrar, Debasmita Saha, Samrat Roy Choudhury

CRISPR/dCas9-KRAB-Mediated Suppression of S100b Restores p53-Mediated Apoptosis in Melanoma Cells

CRISPR/dCas9-KRAB 介导的 S100b 抑制可恢复黑色素瘤细胞中 p53 介导的细胞凋亡

期刊:Cells

影响因子:5.1

doi:10.3390/cells12050730

Samrat Roy Choudhury, Billie Heflin, Erin Taylor, Brian Koss, Nathan L Avaritt, Alan J Tackett

Chemical inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4+ helper and CD8+ effector T cells

DNA-PKcs的化学抑制会损害CD4+辅助性T细胞和CD8+效应性T细胞的活化和细胞毒性。

期刊:Immunology and Cell Biology

影响因子:3.2

doi:10.1111/imcb.12651

Ana C Azevedo-Pouly ，Lauren E Appell ，Lyle Burdine ，Lora J Rogers ，Lauren C Morehead ，Daniel Fil ，Melanie Barker ，Randall R Rainwater ，Zachary J Waldrip ，Brian Koss ，Marie Schluterman Burdine

Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma

白藜芦醇以STING依赖性和非依赖性方式诱导黑色素瘤中主要组织相容性复合体I类抗原呈递

期刊:Molecular Immunology

影响因子:3.2

doi:10.1016/j.molimm.2023.10.003

Lauren C Morehead ，Brian Koss ，Daniel Fil ，Billie Heflin ，Sarita Garg ，Katherine F Wallis ，Alan J Tackett ，Isabelle R Miousse

Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum

磷脂酰乙醇胺的递送可通过靶向内质网减轻暴露于高棕榈酸酯浓度的肝癌细胞的应激反应。

期刊:Cell Death Discovery

影响因子:6.1

doi:10.1038/s41420-020-0241-z

Marcus Trentzsch # ,Eugene Nyamugenda # ,Tiffany K Miles # ,Haven Griffin ,Susan Russell ,Brian Koss ,Kimberly A Cooney ,Kevin D Phelan ,Alan J Tackett ,Srividhya Iyer ,Gunnar Boysen ,Giulia Baldini

Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma

E-钙黏蛋白的缺失抑制CD103的抗肿瘤活性并降低黑色素瘤对免疫检查点阻断疗法的反应性

期刊:Cancer Research

影响因子:12.5

doi:10.1158/0008-5472.CAN-18-1722

Bradley D Shields ，Brian Koss ，Erin M Taylor ，Aaron J Storey ，Kirk L West ，Stephanie D Byrum ，Samuel G Mackintosh ，Rick Edmondson ，Fade Mahmoud ，Sara C Shalin ，Alan J Tackett

Effect of Sulforaphane and 5-Aza-2'-Deoxycytidine on Melanoma Cell Growth

萝卜硫素和5-氮杂-2'-脱氧胞苷对黑色素瘤细胞生长的影响

期刊:Medicines

影响因子:

doi:10.3390/medicines6030071

Tung-Chin Chiang, Brian Koss, L Joseph Su, Charity L Washam, Stephanie D Byrum, Aaron Storey, Alan J Tackett

Indicators of responsiveness to immune checkpoint inhibitors

免疫检查点抑制剂反应指标

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-017-01000-2

Bradley D Shields, Fade Mahmoud, Erin M Taylor, Stephanie D Byrum, Deepanwita Sengupta, Brian Koss, Giulia Baldini, Seth Ransom, Kyle Cline, Samuel G Mackintosh, Ricky D Edmondson, Sara Shalin, Alan J Tackett

免疫

发表日期：2017

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EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma

代谢应激期间 EZH2 的缺失驱动黑色素瘤中 MHC I 类分子机制的恢复

Evolved histone tail regulates 53BP1 recruitment at damaged chromatin

进化的组蛋白尾部调节受损染色质处 53BP1 的募集

Enhancer-activated RET confers protection against oxidative stress to KMT2A-rearranged acute myeloid leukemia

增强子激活的 RET 为 KMT2A 重排的急性髓系白血病提供针对氧化应激的保护

CRISPR/dCas9-KRAB-Mediated Suppression of S100b Restores p53-Mediated Apoptosis in Melanoma Cells

CRISPR/dCas9-KRAB 介导的 S100b 抑制可恢复黑色素瘤细胞中 p53 介导的细胞凋亡

Chemical inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4+ helper and CD8+ effector T cells

DNA-PKcs的化学抑制会损害CD4+辅助性T细胞和CD8+效应性T细胞的活化和细胞毒性。

Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma

白藜芦醇以STING依赖性和非依赖性方式诱导黑色素瘤中主要组织相容性复合体I类抗原呈递

Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum

磷脂酰乙醇胺的递送可通过靶向内质网减轻暴露于高棕榈酸酯浓度的肝癌细胞的应激反应。

Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma

E-钙黏蛋白的缺失抑制CD103的抗肿瘤活性并降低黑色素瘤对免疫检查点阻断疗法的反应性

Effect of Sulforaphane and 5-Aza-2'-Deoxycytidine on Melanoma Cell Growth

萝卜硫素和5-氮杂-2'-脱氧胞苷对黑色素瘤细胞生长的影响

Indicators of responsiveness to immune checkpoint inhibitors

免疫检查点抑制剂反应指标