日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Liver fibrosis is driven by protease-activated receptor-1 expressed by hepatic stellate cells in experimental chronic liver injury

在实验性慢性肝损伤中,肝纤维化是由肝星状细胞表达的蛋白酶激活受体-1 驱动的

Lauren G Poole, Asmita Pant, Holly M Cline-Fedewa, Kurt J Williams, Bryan L Copple, Joseph S Palumbo, James P Luyendyk

Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer

TAM 受体 Axl 和 Mer 对肝脏生理和损伤的差异调节

Anna Zagórska, Paqui G Través, Lidia Jiménez-García, Jenna D Strickland, Joanne Oh, Francisco J Tapia, Rafael Mayoral, Patrick Burrola, Bryan L Copple, Greg Lemke

Dichotomous Role of Plasmin in Regulation of Macrophage Function after Acetaminophen Overdose

纤溶酶在乙酰氨基酚过量后调节巨噬细胞功能的双重作用

Katherine Roth, Jenna Strickland, Nikita Joshi, Meihong Deng, Rebekah C Kennedy, Cheryl E Rockwell, James P Luyendyk, Timothy R Billiar, Bryan L Copple

Hepatic stellate cells orchestrate clearance of necrotic cells in a hypoxia-inducible factor-1α-dependent manner by modulating macrophage phenotype in mice

肝星状细胞通过调节小鼠巨噬细胞表型,以缺氧诱导因子-1α依赖的方式协调坏死细胞的清除

Akie Mochizuki #, Aaron Pace #, Cheryl E Rockwell, Katherine J Roth, Aaron Chow, Kate M O'Brien, Ryan Albee, Kara Kelly, Keara Towery, James P Luyendyk, Bryan L Copple

Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice

骨桥蛋白是小鼠胆管结扎后阻塞性胆汁淤积过程中炎症和肝损伤的初始介质

Min Yang, Anup Ramachandran, Hui-Min Yan, Benjamin L Woolbright, Bryan L Copple, Peter Fickert, Michael Trauner, Hartmut Jaeschke

IL-17A synergistically enhances bile acid-induced inflammation during obstructive cholestasis

IL-17A 协同增强阻塞性胆汁淤积期间胆汁酸诱导的炎症

Kate M O'Brien, Katryn M Allen, Cheryl E Rockwell, Keara Towery, James P Luyendyk, Bryan L Copple

Early growth response factor-1 limits biliary fibrosis in a model of xenobiotic-induced cholestasis in mice

早期生长反应因子-1 限制小鼠外来化合物诱发的胆汁淤积模型中的胆道纤维化

Bradley P Sullivan, Wei Cui, Bryan L Copple, James P Luyendyk

Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice

髓系细胞缺氧诱导因子激活促进胆汁淤积小鼠肝纤维化发展

Bryan L Copple, Sophia Kaska, Callie Wentling

Hypoxia-inducible factor-1α regulates the expression of genes in hypoxic hepatic stellate cells important for collagen deposition and angiogenesis

缺氧诱导因子-1α调节缺氧肝星状细胞中对胶原沉积和血管生成很重要的基因表达

Bryan L Copple, Shan Bai, Lyle D Burgoon, Jeon-Ok Moon

The role of hypoxia-inducible factor-1α in acetaminophen hepatotoxicity

缺氧诱导因子-1α在对乙酰氨基酚肝毒性中的作用

Erica M Sparkenbaugh, Yogesh Saini, Krista K Greenwood, John J LaPres, James P Luyendyk, Bryan L Copple, Jane F Maddox, Patricia E Ganey, Robert A Roth