日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Systematic evaluation of single-cell multimodal data integration enhances cell type resolution and discovery of clinically relevant states in complex tissues

对单细胞多模态数据整合进行系统性评估,可提高细胞类型分辨率,并有助于发现复杂组织中具有临床意义的状态。

Acera-Mateos, Mario; Adiconis, Xian; Li, Jessica-Kanglin; Marchese, Domenica; Caratù, Ginevra; Hon, Chung-Chau; Tiwari, Prabha; Kojima, Miki; Vieth, Beate; Murphy, Michael A; Simmons, Sean K; Lefevre, Thomas; Claes, Irene; O'Connor, Christopher L; Menon, Rajasree; Otto, Edgar A; Ando, Yoshinari; Vandereyken, Katy; Kretzler, Matthias; Bitzer, Markus; Fraenkel, Ernest; Voet, Thierry; Enard, Wolfgang; Carninci, Piero; Heyn, Holger; Levin, Joshua Z; Mereu, Elisabetta

Voltage-gated sodium channels in cancers

癌症中的电压门控钠通道

Liu, Hengrui; Weng, Jieling; Huang, Christopher L-H; Jackson, Antony P

Serum metabolite signatures of cardiac function and morphology in individuals from a population-based cohort

基于人群队列的个体血清代谢物特征与心脏功能和形态的关系

Maushagen, Juliane; Addin, Nuha Shugaa; Schuppert, Christopher; Ward-Caviness, Cavin K; Nattenmüller, Johanna; Adamski, Jerzy; Peters, Annette; Bamberg, Fabian; Schlett, Christopher L; Wang-Sattler, Rui; Rospleszcz, Susanne

Identification of cerebral spinal fluid protein biomarkers in Niemann-Pick disease, type C1

尼曼匹克病 C1 型脑脊液蛋白生物标志物的鉴定

Kiersten Campbell #, Niamh X Cawley #, Rachel Luke, Katelin E J Scott, Nicholas Johnson, Nicole Y Farhat, Derek Alexander, Christopher A Wassif, Wenping Li, Stephanie M Cologna, Elizabeth Berry-Kravis, An Dang Do, Ryan K Dale, Forbes D Porter

Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia

维生素D激活FBP1,从而阻断瓦博格效应并调节急性髓系白血病中的原始细胞代谢。

Xu, Yi; Hino, Christopher; Baylink, David J; Xiao, Jeffrey; Reeves, Mark E; Zhong, Jiang F; Mirshahidi, Saied; Cao, Huynh

Assessment of changes in autophagic vesicles in human immune cell lines exposed to nano particles

评估暴露于纳米颗粒的人类免疫细胞系中自噬囊泡的变化

Christopher A W David, M Estela Del Castillo Busto, Susana Cuello-Nuñez, Heidi Goenaga-Infante, Michael Barrow, David G Fernig, Patricia Murray, Matthew J Rosseinsky, Andrew Owen, Neill J Liptrott

Raptor genomes reveal evolutionary signatures of predatory and nocturnal lifestyles

猛禽基因组揭示了捕食性和夜行性生活方式的进化特征

Cho, Yun Sung; Jun, Je Hoon; Kim, Jung A; Kim, Hak-Min; Chung, Oksung; Kang, Seung-Gu; Park, Jin-Young; Kim, Hwa-Jung; Kim, Sunghyun; Kim, Hee-Jong; Jang, Jin-Ho; Na, Ki-Jeong; Kim, Jeongho; Park, Seung Gu; Lee, Hwang-Yeol; Manica, Andrea; Mindell, David P; Fuchs, Jérôme; Edwards, Jeremy S; Weber, Jessica A; Witt, Christopher C; Yeo, Joo-Hong; Kim, Soonok; Bhak, Jong

Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation

急性髓系白血病患者携带新的生殖系RUNX1突变,其白血病前期和二次突变事件

Ng, Isaac Ks; Lee, Joanne; Ng, Christopher; Kosmo, Bustamin; Chiu, Lily; Seah, Elaine; Mok, Michelle Meng Huang; Tan, Karen; Osato, Motomi; Chng, Wee-Joo; Yan, Benedict; Tan, Lip Kun

Kinomic profiling of glioblastoma cells reveals PLCG1 as a target in restricted glucose

胶质母细胞瘤细胞的动力学分析表明,PLCG1 是限制葡萄糖的靶点

Kiera Walker, Nathaniel H Boyd, Joshua C Anderson, Christopher D Willey, Anita B Hjelmeland

High-performance web services for querying gene and variant annotation

用于查询基因和变异注释的高性能 Web 服务

Xin, Jiwen; Mark, Adam; Afrasiabi, Cyrus; Tsueng, Ginger; Juchler, Moritz; Gopal, Nikhil; Stupp, Gregory S; Putman, Timothy E; Ainscough, Benjamin J; Griffith, Obi L; Torkamani, Ali; Whetzel, Patricia L; Mungall, Christopher J; Mooney, Sean D; Su, Andrew I; Wu, Chunlei