日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Recapitulating physiologically relevant oxygen levels and extracellular matrix remodeling in patient-derived tumor-immune tunable models reveal targeting opportunities for immunologically cold high-grade serous tumors

在患者来源的肿瘤免疫可调模型中重现生理相关的氧水平和细胞外基质重塑，揭示了针对免疫冷型高级别浆液性肿瘤的靶向治疗机会。

期刊:
影响因子:
doi:10.1101/2025.06.23.661098
Plesselova, Simona; Axemaker, Hailey; Calar, Kristin; Isaiah, Oduduabasi; Wollman, Jared; Bhattacharya, Somshuvra; Gnimpieba, Etienne Z; Fink, Darci M; Wang, Congzhou; Bell, Maria; de la Puente, Pilar
细胞生物学
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2025
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Reprogramming of normal fibroblasts into ovarian cancer-associated fibroblasts via non-vesicular paracrine signaling induces an activated fibroblast phenotype

通过非囊泡旁分泌信号将正常成纤维细胞重编程为卵巢癌相关成纤维细胞，可诱导活化成纤维细胞表型

期刊:Biochimica et Biophysica Acta-Molecular Cell Research
影响因子:4.6
doi:10.1016/j.bbamcr.2024.119801
Hailey Axemaker ，Simona Plesselova ，Kristin Calar ，Megan Jorgensen ，Jared Wollman ，Pilar de la Puente
细胞生物学
卵巢癌
肿瘤
囊泡
发育与干细胞
成纤维细胞
肿瘤免疫
信号转导
发表日期：2024
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Multicompartmentalized Microvascularized Tumor-on-a-Chip to Study Tumor-Stroma Interactions and Drug Resistance in Ovarian Cancer

用于研究卵巢癌肿瘤-基质相互作用和耐药性的多室微血管芯片肿瘤模型

期刊:Cellular and Molecular Bioengineering
影响因子:2.3
doi:10.1007/s12195-024-00817-y
Simona Plesselova ，Kristin Calar ，Hailey Axemaker ，Emma Sahly ，Amrita Bhagia ，Jessica L Faragher ，Darci M Fink ，Pilar de la Puente
肿瘤
肿瘤免疫
卵巢癌
发表日期：2024
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The WNK1-ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib.

WNK1-ERK5 通路在卵巢癌的病理生理过程中发挥作用，并限制曲美替尼的治疗效果

期刊:Clinical and Translational Medicine
影响因子:6.8
doi:10.1002/ctm2.1217
Sánchez-Fdez Adrián, Matilla-Almazán Sofía, Montero Juan Carlos, Del Carmen Sofía, Abad Mar, García-Alonso Sara, Bhattacharya Somshuvra, Calar Kristin, de la Puente Pilar, Ocaña Alberto, Pandiella Atanasio, Esparís-Ogando Azucena
肿瘤
卵巢癌
MAPK/ERK
肿瘤免疫
发表日期：2023
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Normal Uterine Fibroblast Are Reprogramed into Ovarian Cancer-Associated Fibroblasts by Ovarian Tumor-derived Conditioned Media

正常子宫成纤维细胞通过卵巢肿瘤衍生的条件培养基重新编程为卵巢癌相关成纤维细胞

期刊:
影响因子:
doi:10.1101/2023.09.29.560158
Hailey Axemaker, Simona Plesselova, Kristin Calar, Megan Jorgensen, Jared Wollman, Pilar de la Puente
肿瘤
卵巢癌
成纤维细胞
发表日期：2023
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Reduction of Metastasis via Epigenetic Modulation in a Murine Model of Metastatic Triple Negative Breast Cancer (TNBC)

通过表观遗传调节减少转移性三阴性乳腺癌 (TNBC) 小鼠模型中的转移

期刊:Cancers
影响因子:
doi:10.3390/cancers14071753
Jessica L S Zylla, Mariah M Hoffman, Simona Plesselova, Somshuvra Bhattacharya, Kristin Calar, Yohannes Afeworki, Pilar de la Puente, Etienne Z Gnimpieba, W Keith Miskimins, Shanta M Messerli
肿瘤
乳腺癌
发表日期：2022
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Mimicking tumor hypoxia and tumor-immune interactions employing three-dimensional in vitro models

利用三维体外模型模拟肿瘤乏氧和肿瘤免疫相互作用

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-020-01583-1
Bhattacharya, Somshuvra; Calar, Kristin; de la Puente, Pilar
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2020
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Bioengineering the Oxygen-Deprived Tumor Microenvironment Within a Three-Dimensional Platform for Studying Tumor-Immune Interactions

在三维平台上构建缺氧肿瘤微环境的生物工程模型，用于研究肿瘤-免疫相互作用

期刊:Frontiers in Bioengineering and Biotechnology
影响因子:4.3
doi:10.3389/fbioe.2020.01040
Somshuvra Bhattacharya ，Kristin Calar ，Claire Evans ，Mark Petrasko ，Pilar de la Puente
肿瘤微环境
免疫/内分泌
肿瘤
肿瘤免疫
发表日期：2020
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Human Plasma-Derived 3D Cultures Model Breast Cancer Treatment Responses and Predict Clinically Effective Drug Treatment Concentrations

人类血浆衍生的 3D 培养物可模拟乳腺癌治疗反应并预测临床有效的药物治疗浓度

期刊:Cancers
影响因子:
doi:10.3390/cancers12071722
Kristin Calar, Simona Plesselova, Somshuvra Bhattacharya, Megan Jorgensen, Pilar de la Puente
肿瘤
乳腺癌
WB
Donkey
IgG
发表日期：2020
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Analysis of Dual Class I Histone Deacetylase and Lysine Demethylase Inhibitor Domatinostat (4SC-202) on Growth and Cellular and Genomic Landscape of Atypical Teratoid/Rhabdoid

双重 I 类组蛋白去乙酰化酶和赖氨酸去甲基化酶抑制剂 Domatinostat (4SC-202) 对非典型畸胎瘤/横纹肌样瘤生长及细胞和基因组景观的分析

期刊:Cancers
影响因子:
doi:10.3390/cancers12030756
Mariah M Hoffman, Jessica S Zylla, Somshuvra Bhattacharya, Kristin Calar, Timothy W Hartman, Ratan D Bhardwaj, W Keith Miskimins, Pilar de la Puente, Etienne Z Gnimpieba, Shanta M Messerli
表观遗传
其它细胞
FCM
IF
IHC-P
WB
FOXM1
发表日期：2020
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