日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Disruption of the human cystin-1 myristoyl-electrostatic switch causes polycystic kidney disease that phenocopies autosomal recessive polycystic kidney disease

人类胱氨酸-1肉豆蔻酰静电开关的破坏会导致多囊肾病,其表型与常染色体隐性多囊肾病相似。

Yang, Chaozhe; Harafuji, Naoe; Watts, Jacob A; Tao, Binli; Moran, Claire; Clements, Jenna; Price, Kalyn; Laucevicius, Anthony; Burrill, Natalie; Gebb, Juliana; Soni, Shelly; Oliver, Edward; Savla, Jill J; Christ, Lori; Moldenhauer, Julie; Hartung, Erum A; Didier, Ryne; Santani, Avni; Sandford, Richard N; Selkirk, Lisa; Radley, Jessica A; Mann, Kathy; Simonicova, Ingrid; Karl, Rudolfo; Kariat Ashraf, Arsila Palliyulla; Wachten, Dagmar; Wilson, Landon; Bebok, Zsuzsanna; Caldovic, Ljubica; Guay-Woodford, Lisa M

The functional impact of 1,570 individual amino acid substitutions in human OTC

1570个氨基酸替换对人类OTC的功能影响

Lo, Russell S; Cromie, Gareth A; Tang, Michelle; Teng, Kevin; Owens, Katherine; Sirr, Amy; Kutz, J Nathan; Morizono, Hiroki; Caldovic, Ljubica; Ah Mew, Nicholas; Gropman, Andrea; Dudley, Aimée M

Differential regulation of MYC expression by PKHD1/Pkhd1 in human and mouse kidneys: phenotypic implications for recessive polycystic kidney disease

PKHD1/Pkhd1 在人类和小鼠肾脏中对 MYC 表达的差异调节:对隐性多囊肾病的表型影响

Naoe Harafuji #, Chaozhe Yang #, Maoqing Wu, Girija Thiruvengadam, Heather Gordish-Dressman, R Griffin Thompson, P Darwin Bell, Avi Z Rosenberg, Claudia Dafinger, Max C Liebau, Zsuzsanna Bebok, Ljubica Caldovic, Lisa M Guay-Woodford

Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells: A mechanistic connection between the kidney defects in cpk mice and human ARPKD

胱氨酸是维持小鼠肾上皮细胞中纤维囊蛋白 (FPC) 水平和保护蛋白质组完整性所必需的:cpk 小鼠肾脏缺陷与人类 ARPKD 之间的机制联系

Yiming J Zhang, Chaozhe Yang, Wei Wang, Naoe Harafuji, Piotr Stasiak, P Darwin Bell, Ljubica Caldovic, Elizabeth Sztul, Lisa M Guay-Woodford, Zsuzsanna Bebok

Transcription factor Ap2b regulates the mouse autosomal recessive polycystic kidney disease genes, Pkhd1 and Cys1

转录因子 Ap2b 调节小鼠常染色体隐性多囊肾病基因 Pkhd1 和 Cys1

Maoqing Wu, Naoe Harafuji, Amber K O'Connor, Ljubica Caldovic, Lisa M Guay-Woodford

Pkhd1cyli/cyli mice have altered renal Pkhd1 mRNA processing and hormonally sensitive liver disease

Pkhd1cyli/cyli 小鼠的肾脏 Pkhd1 mRNA 处理发生了改变,并患上了激素敏感性肝病

Chaozhe Yang, Naoe Harafuji, Ljubica Caldovic, Weiying Yu, Ravindra Boddu, Surajit Bhattacharya, Hayk Barseghyan, Heather Gordish-Dressman, Oded Foreman, Zsuzsa Bebok, Eva M Eicher, Lisa M Guay-Woodford

Fifteen years of urea cycle disorders brain research: Looking back, looking forward

十五年来的尿素循环障碍脑研究:回顾与展望

Sen, Kuntal; Whitehead, Matthew; Castillo Pinto, Carlos; Caldovic, Ljubica; Gropman, Andrea

Assessing Protein Interactions for Clustering of Mitochondrial Urea Cycle Enzymes.

评估蛋白质相互作用以进行线粒体尿素循环酶的聚集

Caldovic Ljubica, Bhuvanendran Shivaprasad, Jaiswal Jyoti

Gene delivery corrects N-acetylglutamate synthase deficiency and enables insights in the physiological impact of L-arginine activation of N-acetylglutamate synthase

基因传递可纠正 N-乙酰谷氨酸合酶缺陷,并能深入了解 L-精氨酸激活 N-乙酰谷氨酸合酶的生理影响

P Sonaimuthu, E Senkevitch, N Haskins, P Uapinyoying, M McNutt, H Morizono, M Tuchman, L Caldovic

A single intravesical instillation of Lactobacillus rhamnosus GG is safe in children and adults with neuropathic bladder: A phase Ia clinical trial

单次膀胱内灌注鼠李糖乳杆菌 GG 对患有神经源性膀胱的儿童和成人是安全的:一项 Ia 期临床试验

Forster, Catherine S; Hsieh, Michael H; Pérez-Losada, Marcos; Caldovic, Ljubica; Pohl, Hans; Ljungberg, Inger; Sprague, Bruce; Stroud, Crystal; Groah, Suzanne