Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
组织来源决定了GOT1依赖性,并赋予放射疗法合成致死性。
期刊:Cancer & Metabolism
影响因子:6
doi:10.1186/s40170-019-0202-2
Barbara S Nelson # ,Lin Lin # ,Daniel M Kremer ,Cristovão M Sousa ,Cecilia Cotta-Ramusino ,Amy Myers ,Johanna Ramos ,Tina Gao ,Ilya Kovalenko ,Kari Wilder-Romans ,Joseph Dresser ,Mary Davis ,Ho-Joon Lee ,Zeribe C Nwosu ,Scott Campit ,Oksana Mashadova ,Brandon N Nicolay ,Zachary P Tolstyka ,Christopher J Halbrook ,Sriram Chandrasekaran ,John M Asara ,Howard C Crawford ,Lewis C Cantley ,Alec C Kimmelman ,Daniel R Wahl ,Costas A Lyssiotis