日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Somatic genetic rescue in ZCCHC8-associated telomere biology disorders

ZCCHC8相关端粒生物学疾病的体细胞遗传拯救

de Tocqueville, Sophie; Donaires, Flavia; DeCleene, Nicholas; Ba, Ibrahima; Nouri, Mina; Kermasson, Laëtitia; Chelbi, Malika; Bergot, Emmanuel; Leblanc, Thierry; Borie, Raphael; Philippot, Quentin; Antone, Elise; Prévot, Grégoire; Blanchard, Elodie; Keren, Boris; Lainey, Elodie; Catto, Marilia; Santana, Barbara; Chandrasekharappa, Settara C; Donovan, Frank X; Bazzo Catto, Luiz Fernando; Callebaut, Isabelle; Young, Neal S; Halfon-Domenech, Carine; Calado, Rodrigo T; Bertuch, Alison A; Gutierrez-Rodrigues, Fernanda; Kannengiesser, Caroline; Revy, Patrick

Intradermal delivery of lipophilic siRNAs enables prolonged skin retention and sustained gene silencing in a porcine model.

在猪模型中,皮内注射亲脂性siRNA可实现皮肤长期滞留和持续基因沉默。

Fakih Hassan H, Zain Ui Abideen Mohammad, Rachid Mohamad Omar, Gross Katherine Y, Ormsby Thomas J R, Ross Vella M, Gagnon Rosemary, Dahlke Christopher, Furgal Raymond C, Lochmann Clemens, Summers Ashley, Sleiman Hanadi F, Fürst Sylvia M, Jackson Shanté N, Gordilho Juliana O, Bouix-Peter Claire, Portal Thibaud, Tang Qi, Harris John E, Khvorova Anastasia, Blanchard Carine, Alterman Julia F

Chronic graft-versus-host disease in long-term survivors of childhood leukemia

儿童白血病长期生存者中的慢性移植物抗宿主病

Saultier, Paul; Michel, Gérard; Sirvent, Anne; Renard, Cécile; Tabone, Marie-Dominique; Leverger, Guy; Baruchel, André; Pochon, Cécile; Paillard, Catherine; Jubert, Charlotte; Ducassou, Stéphane; Poirée, Marilyne; Strullu, Marion; Fahd, Mony; Visentin, Sandrine; Stérin, Arthur; Plantaz, Dominique; Kanold, Justyna; Gandemer, Virginie; Theron, Alexandre; Raus, Nicole; Thouvenin-Doulet, Sandrine; Domenech, Carine; Berbis, Julie; Auquier, Pascal; Dalle, Jean-Hugues

Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine-dependent Tumor Subset Under Metabolic Relationships With CAFs

解码胰腺癌的整合应激反应:识别与癌相关成纤维细胞代谢关系中的丝氨酸依赖性肿瘤亚群

Shin, Sauyeun; Liauzun, Mehdi; Solorzano, Jacobo; Bras, Morgane Le; Jean, Christine; Fourneaux, Benjamin; Dore, Margaux; Fevrier, Lea; Belhabib, Ismahane; Brunel, Alexia; Neuzillet, Cindy; Larroque, Marion; Joffre, Carine; Rocchi, Stephane; Fraunhoffer, Nicolas; Perraud, Aurelie; Mathonnet, Muriel; Pancaldi, Vera; Linares, Laetitia; Iovanna, Juan; Dusetti, Nelson; Larsson, Ola; Nicolle, Remy; Pyronnet, Stephane; Bousquet, Corinne; Martineau, Yvan

The tRNA moieties of both aminoacyl-tRNA substrates of a cyclodipeptide synthase share a common binding site, as revealed by RNA microhelices mimicking tRNA acceptor arms

环二肽合成酶的两个氨酰-tRNA底物的tRNA部分共享一个共同的结合位点,这已通过模拟tRNA受体臂的RNA微螺旋得到证实。

Marouf, Zahra; Tellier-Lebegue, Carine; Glousieau, Matthieu; Morellet, Nelly; Cuniasse, Philippe; Bourand-Plantefol, Alexa; Plancqueel, Stéphane; Mahmoudi, Ikram; Andreani, Jessica; Legrand, Pierre; Ropars, Virginie; Ruedas, Rémi; Hermouet, Léa-Fleur; Moutiez, Mireille; Nhiri, Naïma; Fonvielle, Matthieu; Bressanelli, Stéphane; Katoh, Takayuki; Fernandez Varela, Paloma; Lescop, Ewen; Charbonnier, Jean-Baptiste; Gondry, Muriel

Pre-therapeutic bone marrow-resident leukemic cells in acute myeloid leukemia exhibit a distinct dysregulated calcium signature and stem-like profile reflecting minimal residual disease precursors

急性髓系白血病治疗前骨髓驻留白血病细胞表现出独特的钙失调特征和干细胞样特征,反映了微小残留病灶的前体细胞。

Titah, Sofia; Guillemette, Aurélie; Lewuillon, Clara; Shaik, Faruk Azam; Berthon, Céline; Goursaud, Laure; Tardivel, Meryem; Bongiovanni, Antonino; Chauvet, Paul; Jouy, Nathalie; Peyrouze, Pauline; Cheok, Meyling; Brinster, Carine; Manier, Salomon; Tarhan, Mehmet Çagatay; Lemonnier, Loïc; Quesnel, Bruno; Touil, Yasmine

The 3D architecture of the ctenophore aboral organ and the evolution of complex integrative centers in animals

栉水母反口器官的三维结构及动物复杂整合中心的演化

Ferraioli, Anna; Digel, Leonid; Sturm, Daniela; Colgren, Jeffrey; Le Goff, Carine; Jan, Alexandre; Soto-Angel, Joan J; Naumann, Benjamin; Kittelmann, Maike; Burkhardt, Pawel

Exome sequencing enables molecular diagnosis in 10% of early-onset or familial systemic lupus erythematosus cases

外显子组测序可对 10% 的早发性或家族性系统性红斑狼疮病例进行分子诊断。

Tusseau, Maud; Khaldi-Plassart, Samira; Labalme, Audrey; Mathieu, Anne-Laure; Riller, Quentin; Molitor, Corentin; Simonet, Thomas; Viel, Sebastien; Gaboriaud, Christine; Thielens, Nicole; Heiser, Lionel; Chopin, Emilie; Rouvet, Isabelle; Fabien, Nicole; Goncalves, David; Fremeaux-Bacchi, Véronique; El-Sissy, Carine; Pottier, Nicolas; Larrue, Romain; Ranchin, Bruno; Laurent, Audrey; Fouillet-Desjonqueres, Marine; Jouret, Maurine; Mekinian, Arsène; Yamashita, Motoi; Morio, Tomohiro; Hachulla, Eric; Melki, Isabelle; Kone-Paut, Isabelle; Ballot, Claire; Reumaux, Heloise; Pillet, Pascal; Harambat, Jerome; Richez, Christophe; Richer, Olivier; Hatchuel, Yves; Louillet, Ferielle; Lega, Jean-Christophe; Durieu, Isabelle; Welfringer-Morin, Anne; Picard, Capucine; Messadi, Wassila; Sarrot-Reynauld, Françoise; Sanlaville, Damien; Bader-Meunier, Brigitte; Walzer, Thierry; Lesca, Gaëtan; Rieux-Laucat, Frédéric; Belot, Alexandre

Spherical Skin Model: Stratified Co-Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening.

球形皮肤模型:在球形微珠上进行成纤维细胞和角质形成细胞的分层共培养,用于化合物筛选。

Lenzi Elisa, Vertti-Quintero Nadia, Husson Julien, Bulteau Anne-Laure, Nizard Carine, Pays Karl, Sart Sébastien, Baroud Charles N

The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells

转氨酶-ω-酰胺酶通路感知氧化应激,从而调控内皮细胞中的谷氨酰胺代谢和α-酮戊二酸水平。

Niklas Herrle #,Pedro F Malacarne #,Timothy Warwick,Alfredo Cabrera-Orefice,Yiheng Chen,Maedeh Gheisari,Souradeep Chatterjee,Matthias S Leisegang,Tamim Sarakpi,Sarah Wionski,Melina Lopez,Carine Kader,Tom Teichmann,Maria-Kyriaki Drekolia,Ina Koch,Marcus Keßler,Sabine Klein,Frank Erhard Uschner,Jonel Trebicka,Steffen Brunst,Ewgenij Proschak,Stefan Günther,Mónica Rosas-Lemus,Nina Baumgarten,Stephan Klatt,Thimoteus Speer,Sofia-Iris Bibli,Marta Segarra,Amparo Acker-Palmer,Julian U G Wagner,Ilka Wittig,Stefanie Dimmeler,Marcel H Schulz,J B Richards,Ralf Gilsbach,Travis T Denton,Ingrid Fleming,Luciana Hannibal,Ralf P Brandes #,Flávia Rezende #