Brazilein Impedes IKK Activation by Disrupting RIPK1 Polyubiquitination, Increasing Apoptotic Susceptibility in Cells with Constitutively Active NF-κB.
巴西蛋白酶通过破坏 RIPK1 多聚泛素化来阻碍 IKK 激活,增加组成型活性 NF-κB 细胞的凋亡敏感性。
期刊:Biomolecules & Therapeutics
影响因子:3.2
doi:10.4062/biomolther.2025.099
Park Kyeong Ah, Byun Hee Sun, Ha Jaehee, Kim Chan Sol, Sohn Kyung-Cheol, Shin Sanghee, Park Chan-Yong, Cho Yeon-Jae, Lee Ill Young, Hur Gang Min