日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nanobody-Based Bioconjugates as Potent and Broadly Active Inhibitors of HIV Entry

基于纳米抗体的生物偶联物作为强效且广谱的HIV入侵抑制剂

Saha, Shubhra Jyoti; Kumariya, Rashmi; Davis, Phoenix A; Tourtellott, Emily; Doria-Rose, Nicole; Bewley, Carole A; Cheloha, Ross W

Prolonging parathyroid hormone analog action in vitro and in vivo through peptide lipidation.

通过肽脂化延长甲状旁腺激素类似物在体外和体内的作用

Höppner Jakob, Noda Hiroshi, Anitha Anju Krishnan, Cheloha Ross W, Dean Thomas, Bruce Michael, Brooks Daniel J, Mannstadt Michael, Bouxsein Mary L, Gellman Samuel H, Khatri Ashok, Jüppner Harald, Gardella Thomas J

Generation of Site-Specifically Labeled Affinity Reagents via Use of a Self-Labeling Single Domain Antibody.

利用自标记单域抗体生成位点特异性标记的亲和试剂

Fayn Stanley, Roy Swarnali, Cabalteja Chino C, Lee Woonghee, Makala Hima, Baidoo Kwamena, Nambiar Divya, Sheehan-Klenk Julia, Chung Joon-Yong, Buffington Jesse, Ho Mitchell, Escorcia Freddy E, Cheloha Ross W

Diagnosis and Treatment Response Monitoring of Liver Cancer Using Glypican-3-Targeted Single-Domain Antibody PET

利用靶向糖蛋白聚糖-3的单域抗体PET进行肝癌的诊断和治疗反应监测

Fayn, Stanley; Lee, Woonghee; Basuli, Falguni; Shi, Jianfeng; Makala, Hima; Chung, Joon-Yong; Li, Dan; Nambiar, Divya; Buffington, Jesse; Morhard, Robert; Olkowski, Colleen P; Jacobson, Orit; Wood, Bradford J; Swenson, Rolf E; Cheloha, Ross W; Ho, Mitchell; Choyke, Peter L; Escorcia, Freddy E

Development of bitopic nanobody-ligand conjugates targeting G protein-coupled receptors and exhibiting logic-gated signaling

开发靶向G蛋白偶联受体并表现出逻辑门控信号的双拓扑纳米抗体-配体偶联物

Sachdev, Shivani; Roy, Swarnali; Cheloha, Ross W

Evaluation of AlphaFold modeling for elucidation of nanobody-peptide epitope interactions.

AlphaFold 模型在阐明纳米抗体-肽表位相互作用中的应用评价

Sachdev Shivani, Roy Swarnali, Saha Shubhra J, Zhao Gengxiang, Kumariya Rashmi, Creemer Brendan A, Yin Rui, Pierce Brian G, Bewley Carole A, Cheloha Ross W

Nanobody-based conjugates targeting small molecule-binding GPCRs and exhibiting logic-gated signaling.

基于纳米抗体的偶联物靶向小分子结合GPCR,并表现出逻辑门控信号传导

Sachdev Shivani, Roy Swarnali, Cheloha Ross W

Highly biased agonism for GPCR ligands via nanobody tethering

通过纳米抗体连接实现对GPCR配体的高度偏向性激动作用

Shivani Sachdev ,Brendan A Creemer ,Thomas J Gardella ,Ross W Cheloha

Chemically Induced Dimerization via Nanobody Binding Facilitates in Situ Ligand Assembly and On-Demand GPCR Activation

纳米抗体结合诱导的化学二聚化促进原位配体组装和按需GPCR激活

Saha, Shubhra Jyoti; Cheloha, Ross W

Sortase-mediated labeling: Expanding frontiers in site-specific protein functionalization opens new research avenues

Sortase介导的标记:拓展位点特异性蛋白质功能化的前沿领域,开辟新的研究途径

Braga Emidio, Nayara; Cheloha, Ross W