日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ligand-specific activation trajectories dictate GPCR signalling in cells.

配体特异性激活轨迹决定细胞内的 GPCR 信号传导。

Thomas Romy, Jacoby Pauline S, De Faveri Chiara, Derieux Cécile, Liebing Aenne-Dorothea, Melkes Barbora, Martini Hans-Joachim, Bermúdez Marcel, Stäubert Claudia, Lohse Martin J, Coin Irene, Bock Andreas

Phosphorylation site topology governs the functional dynamics of arrestin recruitment to GPCRs

磷酸化位点拓扑结构决定了阻遏蛋白募集到GPCR的功能动态

Coin, Irene; Müller, Timo; Lee, Woojin; Alkara, Ammar; Baischew, Asat; Aydin, Yasmin; Lam, Jordy; Nagel, Falko; Hoffmann, Carsten; Schulz, Stefan; Sinz, Andrea; Katritch, Vsevolod

Noncanonical Amino Acid Tools and Their Application to Membrane Protein Studies

非典型氨基酸工具及其在膜蛋白研究中的应用

De Faveri, Chiara; Mattheisen, Jordan M; Sakmar, Thomas P; Coin, Irene

Genetically encoded crosslinkers to address protein-protein interactions

利用基因编码交联剂解决蛋白质-蛋白质相互作用问题

Aydin, Yasmin; Coin, Irene

Binding of Natural Peptide Ligands to the Neuropeptide Y(5) Receptor

天然肽配体与神经肽Y(5)受体的结合

Rudolf, Sarina; Kaempf, Kerstin; Vu, Oanh; Meiler, Jens; Beck-Sickinger, Annette G; Coin, Irene

Capturing Peptide-GPCR Interactions and Their Dynamics

捕捉肽-GPCR相互作用及其动态变化

Kaiser, Anette; Coin, Irene

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

优化化学探针在GPCR中的基因整合,用于活体哺乳动物细胞的光交联定位和生物正交化学研究

Serfling, Robert; Seidel, Lisa; Böttke, Thore; Coin, Irene

Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity.

通过邻近增强生物反应性,在蛋白质上添加非天然共价键

Xiang Zheng, Ren Haiyan, Hu Ying S, Coin Irene, Wei Jing, Cang Hu, Wang Lei

Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA pairs

利用细菌氨酰-tRNA合成酶/tRNA对扩展秀丽隐杆线虫的遗传密码

Parrish, Angela R; She, Xingyu; Xiang, Zheng; Coin, Irene; Shen, Zhouxin; Briggs, Steven P; Dillin, Andrew; Wang, Lei

Photo-cross-linkers incorporated into G-protein-coupled receptors in mammalian cells: a ligand comparison

光交联剂掺入哺乳动物细胞的G蛋白偶联受体:配体比较

Coin, Irene; Perrin, Marilyn H; Vale, Wylie W; Wang, Lei