日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Blocking P2X7 receptor with AZ 10606120 exacerbates vascular hyperpermeability and inflammation in murine polymicrobial sepsis

使用 AZ 10606120 阻断 P2X7 受体会加剧小鼠多种微生物脓毒症中的血管通透性过高和炎症

Jamie E Meegan, Padmini Komalavilas, Joyce Cheung-Flynn, Tsz Wing Yim, Nathan D Putz, Jordan J Jesse, Kyle D Smith, Tatiana N Sidorova, Han Noo Ri Lee, Toria Tomasek, Ciara M Shaver, Lorraine B Ware, Colleen M Brophy, Julie A Bastarache

Therapeutic MK2 inhibition blocks pathological vascular smooth muscle cell phenotype switch

治疗性 MK2 抑制剂可阻断病理性血管平滑肌细胞表型转换

J William Tierney, Brian C Evans, Joyce Cheung-Flynn, Bo Wang, Juan M Colazo, Monica E Polcz, Rebecca S Cook, Colleen M Brophy, Craig L Duvall

An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles

一种阴离子内体逃逸聚合物,可增强阳离子肽、生物大分子和纳米颗粒的细胞内递送

Brian C Evans, R Brock Fletcher, Kameron V Kilchrist, Eric A Dailing, Alvin J Mukalel, Juan M Colazo, Matthew Oliver, Joyce Cheung-Flynn, Colleen M Brophy, John W Tierney, Jeffrey S Isenberg, Kurt D Hankenson, Kedar Ghimire, Cynthia Lander, Charles A Gersbach, Craig L Duvall6

Excipients for the lyoprotection of MAPKAP kinase 2 inhibitory peptide nano-polyplexes

用于 MAPKAP 激酶 2 抑制肽纳米复合物冻干保护的赋形剂

Alvin J Mukalel, Brian C Evans, Kameron V Kilchrist, Eric A Dailing, Benjamin Burdette, Joyce Cheung-Flynn, Colleen M Brophy, Craig L Duvall

Heparin-functionalized polymer graft surface eluting MK2 inhibitory peptide to improve hemocompatibility and anti-neointimal activity

肝素功能化聚合物移植物表面洗脱 MK2 抑制肽以改善血液相容性和抗新生内膜活性

Yunki Lee, Phuong Le Thi, Gyeung Mi Seon, Seung Bae Ryu, Colleen M Brophy, YongTae Kim, Jong-Chul Park, Ki Dong Park, Joyce Cheung-Flynn, Hak-Joon Sung

Vascular surgical stretch injury leads to activation of P2X7 receptors and impaired endothelial function

血管手术拉伸损伤导致 P2X7 受体激活和内皮功能受损

Padmini Komalavilas, Weifeng Luo, Christy M Guth, Olukemi Jolayemi, Rachel I Bartelson, Joyce Cheung-Flynn, Colleen M Brophy

Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction

胞质溶胶纳米复合物平台技术用于胞浆肽递送以抑制病理性血管收缩

Brian C Evans, Kyle M Hocking, Kameron V Kilchrist, Eric S Wise, Colleen M Brophy, Craig L Duvall

Surgical vein graft preparation promotes cellular dysfunction, oxidative stress, and intimal hyperplasia in human saphenous vein

手术静脉移植准备促进人类隐静脉的细胞功能障碍、氧化应激和内膜增生

Michael J Osgood, Kyle M Hocking, Igor V Voskresensky, Fan Dong Li, Padmini Komalavilas, Joyce Cheung-Flynn, Colleen M Brophy

Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function

摇动技术形成的大鼠肝细胞球体保持分化的肝细胞基因表达和功能

Colleen M Brophy, Jennifer L Luebke-Wheeler, Bruce P Amiot, Harris Khan, Rory P Remmel, Piero Rinaldo, Scott L Nyberg