日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor

一种用于共价靶向金黄色葡萄球菌毒力因子的mRNA展示方法

Wang, Sijie; Woods, Emily C; Jo, Jeyun; Zhu, Jiyun; Hansel-Harris, Althea; Holcomb, Matthew; Llanos, Manuel; Pedowitz, Nichole J; Upadhyay, Tulsi; Bennett, John; Fellner, Matthias; Park, Ki Wan; Zhang, Anna; Valdez, Tulio A; Forli, Stefano; Chan, Alix I; Cunningham, Christian N; Bogyo, Matthew

Engineered initiator tRNAs can effectively start translation at non-AUG start codons and diversify N-terminal amino acids for mRNA Display

工程化的起始tRNA可以有效地从非AUG起始密码子启动翻译,并使mRNA展示的N端氨基酸多样化。

Helmling, Christina; Chan, Alix I; Cunningham, Christian N

Representation of high-dimensional cell morphology and morphodynamics in 2D latent space.

在二维潜在空间中表示高维细胞形态和形态动力学

Cunningham Christian, Sun Bo

CREMP: Conformer-rotamer ensembles of macrocyclic peptides for machine learning

CREMP:用于机器学习的大环肽构象异构体-旋转异构体集合

Grambow, Colin A; Weir, Hayley; Cunningham, Christian N; Biancalani, Tommaso; Chuang, Kangway V

Hydrogel-Encapsulated Beads Enable Proximity-Driven Encoded Library Synthesis and Screening

水凝胶包裹的微珠可实现邻近驱动的编码文库合成和筛选

Cavett, Valerie; Chan, Alix I; Cunningham, Christian N; Paegel, Brian M

Evaluating Translational Efficiency of Noncanonical Amino Acids to Inform the Design of Druglike Peptide Libraries

评估非天然氨基酸的转化效率以指导类药肽库的设计

Chan, Alix I; Sawant, Manali S; Burdick, Daniel J; Tom, Jeffrey; Song, Aimin; Cunningham, Christian N

Facilitating cell segmentation with the projection-enhancement network

利用投影增强网络促进细胞分割

Eddy, Christopher Z; Naylor, Austin; Cunningham, Christian T; Sun, Bo

Computational Site Saturation Mutagenesis of Canonical and Non-Canonical Amino Acids to Probe Protein-Peptide Interactions

利用计算位点饱和突变技术研究经典和非经典氨基酸对蛋白质-肽相互作用的影响

Holden, Jeffrey K; Pavlovicz, Ryan; Gobbi, Alberto; Song, Yifan; Cunningham, Christian N

Targeting the Hippo Pathway and Cancer through the TEAD Family of Transcription Factors

通过TEAD转录因子家族靶向Hippo通路和癌症

Holden, Jeffrey K; Cunningham, Christian N

Intra- and intermonomer interactions are required to synergistically facilitate ATP hydrolysis in Hsp90

Hsp90中ATP水解需要单体内部和单体之间的相互作用协同促进。

Cunningham, Christian N; Krukenberg, Kristin A; Agard, David A