Daniel Fil相关文献与解析，生知库 | 链接生命科学的每一步

Jacob L Edmondson ，Megan R Reed ，Daniel Fil ，Billie Heflin ，Alyson McKinnon ，Michael A Bauer ，Lauren C Morehead ，Nathan L Avaritt ，Mary Phillips ，Sean D Taverna ，Alan J Tackett ，Brian Koss

代谢

黑色素瘤

EZH2

发表日期：2025

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Design and validation of cell-based potency assays for frataxin supplementation treatments

细胞水平的 Frataxin 补充治疗效力测定的设计和验证

期刊:Molecular Therapy-Methods & Clinical Development

影响因子:

doi:10.1016/j.omtm.2024.101347

Shibani Mukherjee, Larisa Pereboeva, Daniel Fil, Achisha Saikia, Jeon Lee, Jixue Li, M Grazia Cotticelli, Elisabetta Soragni, Robert B Wilson, Marek Napierala, Jill S Napierala

Neurobehavioral deficits of mice expressing a low level of G127V mutant frataxin

表达低水平 G127V 突变型 frataxin 的小鼠的神经行为缺陷

期刊:Neurobiology of Disease

影响因子:5.1

doi:10.1016/j.nbd.2023.105996

Daniel Fil, Robbie L Conley, Aamir R Zuberi, Cathleen M Lutz, Terry Gemelli, Marek Napierala, Jill S Napierala

神经

发表日期：2023

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Plp1 in the enteric nervous system is preferentially expressed during early postnatal development in mouse as DM20, whose expression appears reliant on an intronic enhancer

肠道神经系统中的 Plp1 在小鼠出生后早期发育过程中优先表达为 DM20，其表达似乎依赖于内含子增强子

期刊:Frontiers in Cellular Neuroscience

影响因子:4.2

doi:10.3389/fncel.2023.1175614

Pankaj Patyal, Daniel Fil, Patricia A Wight

PLP1-lacZ transgenic mice reveal that splice variants containing "human-specific" exons are relatively minor in comparison to the archetypal transcript and that an upstream regulatory element bolsters expression during early postnatal brain development

PLP1-lacZ 转基因小鼠发现，与原型转录本相比，含有“人类特异性”外显子的剪接变体相对较小，并且上游调控元件可增强出生后早期大脑发育过程中的表达

期刊:Frontiers in Cellular Neuroscience

影响因子:4.2

doi:10.3389/fncel.2022.1087145

Pankaj Patyal, Daniel Fil, Hamdan Hamdan, Patricia A Wight

Chemical inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4+ helper and CD8+ effector T cells

DNA-PKcs的化学抑制会损害CD4+辅助性T细胞和CD8+效应性T细胞的活化和细胞毒性。

期刊:Immunology and Cell Biology

影响因子:3.2

doi:10.1111/imcb.12651

Ana C Azevedo-Pouly ，Lauren E Appell ，Lyle Burdine ，Lora J Rogers ，Lauren C Morehead ，Daniel Fil ，Melanie Barker ，Randall R Rainwater ，Zachary J Waldrip ，Brian Koss ，Marie Schluterman Burdine

Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma

白藜芦醇以STING依赖性和非依赖性方式诱导黑色素瘤中主要组织相容性复合体I类抗原呈递

期刊:Molecular Immunology

影响因子:3.2

doi:10.1016/j.molimm.2023.10.003

Lauren C Morehead ，Brian Koss ，Daniel Fil ，Billie Heflin ，Sarita Garg ，Katherine F Wallis ，Alan J Tackett ，Isabelle R Miousse

Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models

单、双修饰盐霉素类似物靶向二维和三维乳腺癌模型中的干细胞

期刊:Biomedicine & Pharmacotherapy

影响因子:6.9

doi:10.1016/j.biopha.2021.111815

Alicja Urbaniak, Megan R Reed, Daniel Fil, Anika Moorjani, Sarah Heflin, Michał Antoszczak, Michał Sulik, Adam Huczyński, Michalina Kupsik, Robert L Eoff, Melanie C MacNicol, Timothy C Chambers, Angus M MacNicol

Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia

弗里德赖希共济失调新型 frataxin G127V 点突变小鼠模型来源的细胞的线粒体损伤和衰老表型

期刊:Disease Models & Mechanisms

影响因子:4

doi:10.1242/dmm.045229

Daniel Fil, Balu K Chacko, Robbie Conley, Xiaosen Ouyang, Jianhua Zhang, Victor M Darley-Usmar, Aamir R Zuberi, Cathleen M Lutz, Marek Napierala, Jill S Napierala

Excision of the expanded GAA repeats corrects cardiomyopathy phenotypes of iPSC-derived Friedreich's ataxia cardiomyocytes

切除扩增的 GAA 重复序列可纠正 iPSC 衍生的弗里德赖希共济失调心肌细胞的心肌病表型

期刊:Stem Cell Research

影响因子:0.8

doi:10.1016/j.scr.2019.101529

Jixue Li, Natalia Rozwadowska, Amanda Clark, Daniel Fil, Jill S Napierala, Marek Napierala

EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma

代谢应激期间 EZH2 的缺失驱动黑色素瘤中 MHC I 类分子机制的恢复

Design and validation of cell-based potency assays for frataxin supplementation treatments

细胞水平的 Frataxin 补充治疗效力测定的设计和验证

Neurobehavioral deficits of mice expressing a low level of G127V mutant frataxin

表达低水平 G127V 突变型 frataxin 的小鼠的神经行为缺陷

Plp1 in the enteric nervous system is preferentially expressed during early postnatal development in mouse as DM20, whose expression appears reliant on an intronic enhancer

肠道神经系统中的 Plp1 在小鼠出生后早期发育过程中优先表达为 DM20，其表达似乎依赖于内含子增强子

PLP1-lacZ transgenic mice reveal that splice variants containing "human-specific" exons are relatively minor in comparison to the archetypal transcript and that an upstream regulatory element bolsters expression during early postnatal brain development

PLP1-lacZ 转基因小鼠发现，与原型转录本相比，含有“人类特异性”外显子的剪接变体相对较小，并且上游调控元件可增强出生后早期大脑发育过程中的表达

Chemical inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4+ helper and CD8+ effector T cells

DNA-PKcs的化学抑制会损害CD4+辅助性T细胞和CD8+效应性T细胞的活化和细胞毒性。

Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma

白藜芦醇以STING依赖性和非依赖性方式诱导黑色素瘤中主要组织相容性复合体I类抗原呈递

Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models

单、双修饰盐霉素类似物靶向二维和三维乳腺癌模型中的干细胞

Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia

弗里德赖希共济失调新型 frataxin G127V 点突变小鼠模型来源的细胞的线粒体损伤和衰老表型

Excision of the expanded GAA repeats corrects cardiomyopathy phenotypes of iPSC-derived Friedreich's ataxia cardiomyocytes

切除扩增的 GAA 重复序列可纠正 iPSC 衍生的弗里德赖希共济失调心肌细胞的心肌病表型