日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Muscarinic acetylcholine type 1 receptor antagonism activates TRPM3 to augment mitochondrial function and drive axonal repair in adult sensory neurons

毒蕈碱型乙酰胆碱1型受体拮抗作用激活TRPM3,从而增强线粒体功能并促进成年感觉神经元的轴突修复。

Sanjana Chauhan ,Darrell R Smith ,Shiva Shariati-Ievari ,Abhay Srivastava ,Sanjiv Dhingra ,Michel Aliani ,Paul Fernyhough

CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth

CEBPβ 调节成人感觉神经元中的内源性 IGF-1,可以克服糖尿病引起的生物能量学和轴突生长缺陷

Mohamad-Reza Aghanoori, Prasoon Agarwal, Evan Gauvin, Raghu S Nagalingam, Raiza Bonomo, Vinith Yathindranath, Darrell R Smith, Yan Hai, Samantha Lee, Corinne G Jolivalt, Nigel A Calcutt, Meaghan J Jones, Michael P Czubryt, Donald W Miller, Vernon W Dolinsky, Virginie Mansuy-Aubert, Paul Fernyhough

Sensory neurons derived from diabetic rats exhibit deficits in functional glycolysis and ATP that are ameliorated by IGF-1

糖尿病大鼠的感觉神经元表现出功能性糖酵解和 ATP 缺陷,而 IGF-1 可以改善这种情况

Mohamad-Reza Aghanoori, Vicky Margulets, Darrell R Smith, Lorrie A Kirshenbaum, Daniel Gitler, Paul Fernyhough

Muscarinic Toxin 7 Signals Via Ca2+/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration

毒蕈碱毒素 7 通过 Ca2+/钙调蛋白依赖性蛋白激酶激酶 β 发出信号,增强线粒体功能并预防神经退行性

Ali Saleh, Mohammad Golam Sabbir, Mohamad-Reza Aghanoori, Darrell R Smith, Subir K Roy Chowdhury, Lori Tessler, Jennifer Brown, Eva Gedarevich, Markos Z Kassahun, Katie Frizzi, Nigel A Calcutt, Paul Fernyhough

Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes

胰岛素样生长因子-1 激活 AMPK 以增强线粒体功能并纠正 1 型糖尿病中感觉神经元的神经元代谢

Mohamad-Reza Aghanoori, Darrell R Smith, Shiva Shariati-Ievari, Andrew Ajisebutu, Annee Nguyen, Fiona Desmond, Carlos H A Jesus, Xiajun Zhou, Nigel A Calcutt, Michel Aliani, Paul Fernyhough

Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy

选择性拮抗毒蕈碱受体对周围神经病变有神经保护作用

Nigel A Calcutt, Darrell R Smith, Katie Frizzi, Mohammad Golam Sabbir, Subir K Roy Chowdhury, Teresa Mixcoatl-Zecuatl, Ali Saleh, Nabeel Muttalib, Randy Van der Ploeg, Joseline Ochoa, Allison Gopaul, Lori Tessler, Jürgen Wess, Corinne G Jolivalt, Paul Fernyhough