日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Predicting microcystin concentration action-level exceedances resulting from cyanobacterial blooms in selected lake sites in Ohio

预测俄亥俄州部分湖泊蓝藻水华导致的微囊藻毒素浓度超标情况

期刊:Environmental Monitoring and Assessment
影响因子:3
doi:10.1007/s10661-020-08407-x
Francy, Donna S; Brady, Amie M G; Stelzer, Erin A; Cicale, Jessica R; Hackney, Courtney; Dalby, Harrison D; Struffolino, Pamela; Dwyer, Daryl F
发表日期：2020
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Discovery of imidazo[1,2-a]-, [1,2,4]triazolo[4,3-a]-, and [1,2,4]triazolo[1,5-a]pyridine-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5

发现咪唑并[1,2-a]-、[1,2,4]三唑并[4,3-a]-和[1,2,4]三唑并[1,5-a]吡啶-8-甲酰胺类化合物是代谢型谷氨酸受体亚型5的负变构调节剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2017.09.042
Felts, Andrew S; Rodriguez, Alice L; Morrison, Ryan D; Bollinger, Katrina A; Venable, Daryl F; Blobaum, Anna L; Byers, Frank W; Thompson Gray, Analisa; Daniels, J Scott; Niswender, Colleen M; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W; Emmitte, Kyle A
信号转导
代谢
发表日期：2017
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N-Alkylpyrido[1',2':1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodents

N-烷基吡啶并[1',2':1,5]吡唑并[4,3-d]嘧啶-4-胺：一类新型的mGlu1/5负变构调节剂，可在啮齿动物中枢神经系统暴露后发挥作用

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2016.03.026
Felts, Andrew S; Rodriguez, Alice L; Morrison, Ryan D; Venable, Daryl F; Blobaum, Anna L; Byers, Frank W; Daniels, J Scott; Niswender, Colleen M; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W; Emmitte, Kyle A
神经科学
发表日期：2016
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Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenics

对源自精神分裂症患者体内有害 GRM1 突变的突变型 mGlu1 受体进行化学调节

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/cb500560h
Cho, Hyekyung P; Garcia-Barrantes, Pedro M; Brogan, John T; Hopkins, Corey R; Niswender, Colleen M; Rodriguez, Alice L; Venable, Daryl F; Morrison, Ryan D; Bubser, Michael; Daniels, J Scott; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W
信号转导
精神分裂症
神经科学
发表日期：2014
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Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety

VU0431316 的发现：一种 mGlu5 的负变构调节剂，在焦虑小鼠模型中具有活性。

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2014.06.003
Bates, Brittney S; Rodriguez, Alice L; Felts, Andrew S; Morrison, Ryan D; Venable, Daryl F; Blobaum, Anna L; Byers, Frank W; Lawson, Kera P; Daniels, J Scott; Niswender, Colleen M; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W; Emmitte, Kyle A
发表日期：2014
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Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addiction

取代的1-苯基-3-(吡啶-2-基)脲类mGlu5负变构调节剂：发现一种新型工具化合物VU0463841，该化合物在可卡因成瘾大鼠模型中具有活性。

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/cn400070k
Amato, Russell J; Felts, Andrew S; Rodriguez, Alice L; Venable, Daryl F; Morrison, Ryan D; Byers, Frank W; Daniels, J Scott; Niswender, Colleen M; Conn, P Jeffrey; Lindsley, Craig W; Jones, Carrie K; Emmitte, Kyle A
Rat
发表日期：2013
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N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in rats

N-酰基-N'-芳基哌嗪作为 mGlu1 的负变构调节剂：鉴定 VU0469650，一种在大鼠中枢神经系统中具有暴露作用的强效选择性工具化合物

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.5
doi:10.1016/j.bmcl.2013.05.020
Kimberly M Lovell, Andrew S Felts, Alice L Rodriguez, Daryl F Venable, Hyekyung P Cho, Ryan D Morrison, Frank W Byers, J Scott Daniels, Colleen M Niswender, P Jeffrey Conn, Craig W Lindsley, Kyle A Emmitte
神经
发表日期：2013
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Octahydropyrrolo[3,4-c]pyrrole negative allosteric modulators of mGlu1

八氢吡咯并[3,4-c]吡咯类化合物是mGlu1的负变构调节剂。

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2013.07.029
Manka, Jason T; Rodriguez, Alice L; Morrison, Ryan D; Venable, Daryl F; Cho, Hyekyung P; Blobaum, Anna L; Daniels, J Scott; Niswender, Colleen M; Conn, P Jeffrey; Lindsley, Craig W; Emmitte, Kyle A
发表日期：2013
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Discovery of VU0409106: A negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety

VU0409106 的发现：一种 mGlu5 的负变构调节剂，在焦虑小鼠模型中具有活性。

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2013.09.001
Felts, Andrew S; Rodriguez, Alice L; Morrison, Ryan D; Venable, Daryl F; Manka, Jason T; Bates, Brittney S; Blobaum, Anna L; Byers, Frank W; Daniels, J Scott; Niswender, Colleen M; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W; Emmitte, Kyle A
发表日期：2013
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Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonists

在 ADX-47273 mGlu5 PAM 支架中发现分子开关，这些开关可调节药理学模式，从而产生强效的 mGlu5 NAM、PAM 和部分拮抗剂。

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2010.11.119
Lamb, Jeffrey P; Engers, Darren W; Niswender, Colleen M; Rodriguez, Alice L; Venable, Daryl F; Conn, P Jeffrey; Lindsley, Craig W
发表日期：2011
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