日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer's disease profile and possible mechanisms of disease protection

单核 RNA 测序证实了常染色体显性阿尔茨海默病的特征以及可能的疾病保护机制

Maria Camila Almeida, Sarah J Eger, Caroline He, Morgane Audouard, Arina Nikitina, Stella M K Glasauer, Dasol Han, Barbara Mejía-Cupajita, Juliana Acosta-Uribe, Nelson David Villalba-Moreno, Jessica Lisa Littau, Megan Elcheikhali, Erica Keane Rivera, Daniel Carneiro Carrettiero, Carlos Andrés Villeg

An explainable map of human gastruloid morphospace reveals gastrulation failure modes and predicts teratogens

可解释的人类原肠胚形态空间图揭示了原肠胚形成失败模式并预测了致畸剂

Joseph Rufo, Chongxu Qiu, Dasol Han, Naomi Baxter, Gabrielle Daley, Maxwell Z Wilson

ZBTB12 is a molecular barrier to dedifferentiation in human pluripotent stem cells

ZBTB12是人类多能干细胞去分化的分子屏障

Dasol Han # ,Guojing Liu # ,Yujeong Oh # ,Seyoun Oh ,Seungbok Yang ,Lori Mandjikian ,Neha Rani ,Maria C Almeida ,Kenneth S Kosik ,Jiwon Jang

Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate

压力通过 BAG2 泛素依赖性降解缩合物将客户端引导至蛋白酶体

Daniel C Carrettiero, Maria C Almeida, Andrew P Longhini, Jennifer N Rauch, Dasol Han, Xuemei Zhang, Saeed Najafi, Jason E Gestwicki, Kenneth S Kosik

Dynamic assembly of the mRNA m6A methyltransferase complex is regulated by METTL3 phase separation

mRNA m6A 甲基转移酶复合物的动态组装受 METTL3 相分离调控

Dasol Han, Andrew P Longhini, Xuemei Zhang, Vivian Hoang, Maxwell Z Wilson, Kenneth S Kosik

YAP inhibits HCMV replication by impairing STING-mediated nuclear transport of the viral genome

YAP 通过损害 STING 介导的病毒基因组核运输来抑制 HCMV 复制

Ju Hyun Lee, Mookwang Kwon, Woo Young Lim, Chae Rin Yoo, Youngik Yoon, Dasol Han, Jin-Hyun Ahn, Keejung Yoon

Nucleation of the destruction complex on the centrosome accelerates degradation of β-catenin and regulates Wnt signal transmission

破坏复合物在着丝粒上的成核加速β-catenin的降解并调节Wnt信号传递

Ryan S Lach, Chongxu Qiu, Erfan Zeyaei Kajbaf, Naomi Baxter, Dasol Han, Alex Wang, Hannah Lock, Orlando Chirikian, Beth Pruitt, Maxwell Z Wilson

Non-cell autonomous promotion of astrogenesis at late embryonic stages by constitutive YAP activation

通过组成性 YAP 激活非细胞自主促进晚期胚胎星形细胞发生

Dasol Han #, Mookwang Kwon #, Sun Min Lee, Samuel J Pleasure, Keejung Yoon

Control over single-cell distribution of G1 lengths by WNT governs pluripotency

WNT 控制单细胞 G1 长度分布,调控多能性

Jiwon Jang, Dasol Han, Mahdi Golkaram, Morgane Audouard, Guojing Liu, Daniel Bridges, Stefan Hellander, Alex Chialastri, Siddharth S Dey, Linda R Petzold, Kenneth S Kosik

Ttyh1 regulates embryonic neural stem cell properties by enhancing the Notch signaling pathway

Ttyh1通过增强Notch信号通路调控胚胎神经干细胞特性

Juwan Kim, Dasol Han, Sung-Hyun Byun, Mookwang Kwon, Jae Youl Cho, Samuel J Pleasure, Keejung Yoon