日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanical compression induces neuronal apoptosis, reduces synaptic activity, and promotes glial neuroinflammation in mice and humans.

机械压缩可诱导小鼠和人类神经元凋亡,降低突触活性,并促进神经胶质炎症。

Zarodniuk Maksym, Wenninger Anna, Najera Julian, Lee Jihaeng, Markillie Jack, MacKenzie Cameron, Bergqvist-Patzke Jenny, Batista Bianca, Panchbhavi Megna, Rumbach R'nld, Burchett Alice, Sander Charles, Datta Meenal, Patzke Christopher

Leveraging insights from cancer to improve tuberculosis therapy

利用癌症研究的成果来改进结核病治疗

Datta, Meenal; Via, Laura E; Dartois, Véronique; Xu, Lei; Barry, Clifton E 3rd; Jain, Rakesh K

Solid Stress Estimations via Intraoperative 3D Navigation in Patients with Brain Tumors

利用术中三维导航技术对脑肿瘤患者进行实体应力估计

Nia, Hadi T; Datta, Meenal; Kumar, Ashwin S; Siri, Saeed; Ferraro, Gino B; Chatterjee, Sampurna; McHugh, Jeffrey M; Ng, Patrick R; West, Timothy R; Rapalino, Otto; Choi, Bryan D; Nahed, Brian V; Munn, Lance L; Jain, Rakesh K

Wnt inhibition alleviates resistance to anti-PD1 therapy and improves antitumor immunity in glioblastoma

Wnt抑制可减轻胶质母细胞瘤对PD-1抑制剂的耐药性并增强其抗肿瘤免疫力。

Krishnan, Shanmugarajan; Lee, Somin; Amoozgar, Zohreh; Subudhi, Sonu; Srinivasan Kumar, Ashwin; Posada, Jessica M; Lindeman, Neal; Lei, Pinji; Duquette, Mark; Steinbuch, Sophie; Charabati, Marc; Huang, Peigen; Andersson, Patrik; Datta, Meenal; Munn, Lance L; Fukumura, Dai; Jain, Rakesh K

Chronic compression induces transcriptional, metabolic, and functional state changes in macrophages that recapitulate tumor-associated phenotypes

慢性压迫可诱导巨噬细胞发生转录、代谢和功能状态的改变,从而重现肿瘤相关表型。

Burchett Darantiere, Alice; Chen, Hao; Najera, Julian; Howard, Scott; Datta, Meenal

Histone deacetylase inhibitors sensitize glioblastoma models to temozolomide and reprogram immunosuppressive myeloid cells

组蛋白去乙酰化酶抑制剂可增强胶质母细胞瘤模型对替莫唑胺的敏感性,并重编程免疫抑制性髓系细胞

Asaadi Tehrani, Golnaz; Kubick, Becca; Zarodniuk, Maksym; Datta, Meenal

Chronic compression drives macrophages toward a pathological pro-tumor state.

慢性压迫会促使巨噬细胞向病理性的促肿瘤状态发展

Burchett Alice, Chen Hao, Najera Julian, Howard Scott, Datta Meenal

Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast cancer peritumoral microenvironments.

即时荧光寿命成像显微镜揭示了乳腺癌肿瘤周围微环境中基质细胞的机械代谢重编程

Najera Julian, Chen Hao, Batista Bianca, Ketchum Frank, Ali Aktar, Zorlutuna Pinar, Howard Scott, Datta Meenal

Ratiometric near-infrared fluorescent probe for nitroreductase activity enables 3D imaging of hypoxic cells within intact tumor spheroids

用于检测硝基还原酶活性的比例式近红外荧光探针能够对完整肿瘤球体内的乏氧细胞进行三维成像

Morsby, Janeala J; Zhang, Zhumin; Burchett, Alice; Datta, Meenal; Smith, Bradley D

Mathematical model of oxygen, nutrient, and drug transport in tuberculosis granulomas

结核肉芽肿中氧气、营养物质和药物运输的数学模型

Datta, Meenal; Kennedy, McCarthy; Siri, Saeed; Via, Laura E; Baish, James W; Xu, Lei; Dartois, Véronique; Barry, Clifton E 3rd; Jain, Rakesh K