日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes

肝素酶抑制作为保护内皮糖萼和预防糖尿病微血管并发症的系统方法

期刊:Cardiovascular Diabetology
影响因子:8.5
doi:10.1186/s12933-024-02133-1
Monica Gamez, Hesham E Elhegni, Sarah Fawaz, Kwan Ho Ho, Neill W Campbell, David A Copland, Karen L Onions, Matthew J Butler, Elizabeth J Wasson, Michael Crompton, Raina D Ramnath, Yan Qiu, Yu Yamaguchi, Kenton P Arkill, David O Bates, Jeremy E Turnbull, Olga V Zubkova, Gavin I Welsh, Denize Atan, S
代谢
糖尿病
ELISA
ICC
IP
VSV-G Tag
发表日期：2024
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The role of mesenchymal cells in cholangiocarcinoma

间充质细胞在胆管癌中的作用

期刊:Disease Models & Mechanisms
影响因子:4
doi:10.1242/dmm.050716
Mireia Sueca-Comes, Elena Cristina Rusu, Jennifer C Ashworth, Pamela Collier, Catherine Probert, Alison Ritchie, Marian Meakin, Nigel P Mongan, Isioma U Egbuniwe, Jesper Bøje Andersen, David O Bates, Anna M Grabowska
免疫
细胞生物学
胆管癌
肿瘤细胞
PCR
发表日期：2024
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Targeting alternative splicing as a new cancer immunotherapy-phosphorylation of serine arginine-rich splicing factor (SRSF1) by SR protein kinase 1 (SRPK1) regulates alternative splicing of PD1 to generate a soluble antagonistic isoform that prevents T cell exhaustion

以选择性剪接为目标作为一种新的癌症免疫疗法——SR 蛋白激酶 1 (SRPK1) 对富含丝氨酸精氨酸的剪接因子 (SRSF1) 进行磷酸化，从而调节 PD1 的选择性剪接，产生一种可溶性拮抗异构体，防止 T 细胞耗竭

期刊:Cancer Immunology Immunotherapy
影响因子:8.1
doi:10.1007/s00262-023-03534-z
Mussarat Wahid, Benjamart Pratoomthai, Isioma U Egbuniwe, Hannah R Evans, Roya Babaei-Jadidi, Jason O Amartey, Viola Erdelyi, Kiren Yacqub-Usman, Andrew M Jackson, Jonathan C Morris, Poulam M Patel, David O Bates
肿瘤
表观遗传
T细胞
发表日期：2023
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Elevated PLAUR is observed in the airway epithelium of asthma patients and blocking improves barrier integrity

在哮喘患者的气道上皮中观察到 PLAUR 升高，阻断可改善屏障完整性

期刊:Clinical and Translational Allergy
影响因子:4.6
doi:10.1002/clt2.12293
Michael A Portelli, Sangita Bhaker, Vincent Pang, David O Bates, Simon R Johnson, Andrew P Mazar, Dominick Shaw, Christopher Brightling, Ian Sayers
免疫
哮喘
发表日期：2023
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Vascular endothelial growth factor isoforms differentially protect neurons against neurotoxic events associated with Alzheimer's disease

血管内皮生长因子亚型以不同的方式保护神经元免受与阿尔茨海默病相关的神经毒性事件的影响

期刊:Frontiers in Molecular Neuroscience
影响因子:3.5
doi:10.3389/fnmol.2023.1181626
Roaa H Alalwany, Tom Hawtrey, Kevin Morgan, Jonathan C Morris, Lucy F Donaldson, David O Bates
神经
阿尔茨海默症
发表日期：2023
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Preclinical evidence for anaplastic lymphoma kinase inhibitors as novel therapeutic treatments for cholangiocarcinoma

间变性淋巴瘤激酶抑制剂作为胆管癌新型治疗方法的临床前证据

期刊:Frontiers in Oncology
影响因子:3.5
doi:10.3389/fonc.2023.1184900
Kyaw Zwar Myint,Mireia Sueca-Comes,Pamela Collier,Brinda Balasubramanian,Simran Venkatraman,John Gordan,Abed M Zaitoun,Abhik Mukherjee,Arvind Arora,Noppadol Larbcharoensub,Chinnawut Suriyonplengsaeng,Kanokpan Wongprasert,Tavan Janvilisri,Dhanny Gomez,Anna M Grabowska,Rutaiwan Tohtong,David O Bates,Kiren Yacqub-Usman
淋巴瘤
胆管癌
肿瘤
发表日期：2023
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Targeting FGFRs Using PD173074 as a Novel Therapeutic Strategy in Cholangiocarcinoma

使用 PD173074 靶向 FGFR 作为胆管癌的新型治疗策略

期刊:Cancers
影响因子:
doi:10.3390/cancers15092528
Brinda Balasubramanian, Kiren Yacqub-Usman, Simran Venkatraman, Kyaw Zwar Myint, Jitlada Juengsamarn, Poowanai Sarkhampee, Nithi Lertsawatvicha, Jittiyawadee Sripa, Thiti Kuakpaetoon, Chinnawut Suriyonplengsaeng, Kanokpan Wongprasert, Anna M Grabowska, David O Bates, Tavan Janvilisri, Rutaiwan Tohto
肿瘤
胆管癌
发表日期：2023
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Hypoxia-induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain

缺氧诱导碳酸酐酶介导背角神经元激活并诱发神经性疼痛

期刊:Pain
影响因子:5.9
doi:10.1097/j.pain.0000000000002627
Marlene E Da Vitoria Lobo, Nick Weir, Lydia Hardowar, Yara Al Ojaimi, Ryan Madden, Alex Gibson, Samuel M Bestall, Masanori Hirashima, Chris B Schaffer, Lucy F Donaldson, David O Bates, Richard Philip Hulse
信号转导
神经
发表日期：2022
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Serine-arginine-rich protein kinase-1 inhibition for the treatment of diabetic retinopathy

富含丝氨酸-精氨酸的蛋白激酶-1抑制剂用于治疗糖尿病视网膜病变

期刊:American Journal of Physiology-Heart and Circulatory Physiology
影响因子:4.1
doi:10.1152/ajpheart.00001.2022
Naseeb K Malhi, Claire L Allen, Elizabeth Stewart, Katherine L Horton, Federica Riu, Jennifer Batson, Winfried Amoaku, Jonathan C Morris, Kenton P Arkill, David O Bates
代谢
糖尿病
发表日期：2022
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A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties

使用剪接敏感荧光报告基因的药物重新定位筛选可识别具有抗血管生成特性的 VEGF-A 剪接的新型调节剂

期刊:Oncogenesis
影响因子:5.9
doi:10.1038/s41389-021-00323-0
Eleanor Star #, Megan Stevens #, Clare Gooding, Christopher W J Smith, Ling Li, Monica Lamici Ayine, Steve J Harper, David O Bates, Sebastian Oltean
心血管
Angiogenesis
发表日期：2021
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