日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Covalent aptamers: agents with promising therapeutic and diagnostic potential

共价适体:具有广阔治疗和诊断前景的试剂

Albright, Savannah; Boette, Jessica; Cacace, Mary; Deiters, Alexander

Optogenetics with Atomic Precision─A Comprehensive Review of Optical Control of Protein Function through Genetic Code Expansion

原子级精度的光遗传学——通过遗传密码扩展实现蛋白质功能的光学控制的综合综述

Charette, Maura; Rosenblum, Carolyn; Shade, Olivia; Deiters, Alexander

Small-molecule control of CAR T cells

小分子对CAR-T细胞的控制

Adams, Eric L; McGovern, Andrew C; So, Victor; Srinivasan, Sneha; Deiters, Alexander; Lohmueller, Jason

Difunctional oxidatively cleavable alkenyl boronates: application to cellular peroxide sensing from a fluorophore-quencher pair

双功能氧化裂解烯基硼酸酯:应用于荧光团-猝灭剂对的细胞过氧化物检测

Klootwyk, Brittany M; Fleury, Grace M; Albright, Savannah; Deiters, Alexander; Floreancig, Paul E

Conditional Control of Benzylguanine Reaction with the Self-Labeling SNAP-tag Protein.

利用自标记 SNAP 标签蛋白对苄基鸟嘌呤反应进行条件控制

Caldwell Steven E, Demyan Isabella R, Falcone Gianna N, Parikh Avani, Lohmueller Jason, Deiters Alexander

Rational Design of Stapled Covalent Peptide Modifiers of Oncoprotein E6 from Human Papillomavirus.

人乳头瘤病毒癌蛋白 E6 的交联共价肽修饰剂的合理设计

Emanuelson Cole, Naro Yuta, Shade Olivia, Liu Melinda, Khare Sagar D, Deiters Alexander

Inverted Molecular Beacons as Reaction-Based Hybridization Probes for Small-Molecule Activation by Nucleic Acid Inputs.

反向分子信标作为基于反应的杂交探针,用于通过核酸输入激活小分子

Emanuelson Cole, Bardhan Anirban, Ankenbruck Nicholas, Boette Jessica, Deiters Alexander

Investigating protein degradability through site-specific ubiquitin ligase recruitment

通过位点特异性泛素连接酶募集研究蛋白质降解性

Shade, Olivia; Ryan, Amy; Belsito, Gabriella; Deiters, Alexander

Time-Resolved Crystallography Reveals the Mechanisms of GTP hydrolysis for N-RAS and the Oncogenic Mutants G12C, G12V and Q61L

时间分辨晶体学揭示了N-RAS及其致癌突变体G12C、G12V和Q61L的GTP水解机制

Lin, Guowu; Zinser-Peniche, Paola; Zhou, Xiaohong; Santiago, Ulises; Kurnikov, Igor; Russi, Silvia; Chagas, Brisa; Sharpe, May E; Stegmann, Dennis P; Heinig, Shannon A; Goyal, Rohan K; Nagarajan, V; Calero, Daniel; Vergara, Sandra; Deiters, Alexander; Kurnikova, Maria G; Burns, Timothy F; Cohen, Aina; Calero, Guillermo

Potent and Selective Oxidatively Labile Ether-Based Prodrugs through Late-Stage Boronate Incorporation

通过后期硼酸酯引入制备高效且选择性的氧化不稳定醚基前药

Geaneotes, Paul J; Janosko, Chasity P; Afeke, Cephas; Deiters, Alexander; Floreancig, Paul E