日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice

小鼠小胶质细胞中与 ALS/FTD 相关的 TBK1 缺陷会诱导类似衰老的小胶质细胞特征,并导致小鼠社交识别缺陷。

Isadora Lenoel,Matthieu Ribon,Félicie Lorenc,Aurélien Diebold,Clementine E Philibert,David Robaldo,Manel Badsi,Julianne Perronnet,Julie Lameth,Felix Berriat,Hidemi Misawa,Marie Coutelier,Raphaelle Cassel,Nadège Sarrazin,Coline Jost-Mousseau,Delphine Bohl,Stéphanie Millecamps,Michel Mallat,David Brenner,Jochen H Weishaupt,Séverine Boillée,Christian S Lobsiger

Enhanced secretion of the amyotrophic lateral sclerosis ALS-associated misfolded TDP-43 mediated by the ER-ubiquitin specific peptidase USP19

ER-泛素特异性肽酶 USP19 介导肌萎缩侧索硬化症 (ALS) 相关错误折叠的 TDP-43 分泌增强

Flavien Picard, Takashi Nonaka #, Edwige Belotti #, Alexis Osseni, Elisabeth Errazuriz-Cerda, Coline Jost-Mousseau, Emilien Bernard, Agnès Conjard-Duplany, Delphine Bohl, Masato Hasegawa, Cédric Raoul, Thierry Galli, Laurent Schaeffer, Pascal Leblanc1

A conserved NR5A1-responsive enhancer regulates SRY in testis-determination

保守的NR5A1反应增强子在睾丸决定中调节SRY

Denis Houzelstein, Caroline Eozenou, Carlos F Lagos, Maëva Elzaiat, Joelle Bignon-Topalovic, Inma Gonzalez, Vincent Laville, Laurène Schlick, Somboon Wankanit, Prochi Madon, Jyotsna Kirtane, Arundhati Athalye, Federica Buonocore, Stéphanie Bigou, Gerard S Conway, Delphine Bohl, John C Achermann, Anu

The temporal balance between self-renewal and differentiation of human neural stem cells requires the amyloid precursor protein

人类神经干细胞自我更新和分化之间的时间平衡需要淀粉样蛋白前体

Khadijeh Shabani, Julien Pigeon, Marwan Benaissa Touil Zariouh, Tengyuan Liu, Azadeh Saffarian, Jun Komatsu, Elise Liu, Natasha Danda, Mathilde Becmeur-Lefebvre, Ridha Limame, Delphine Bohl, Carlos Parras, Bassem A Hassan

Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth

基于结构的病毒肽中PDZ结合基序优化可刺激神经突生长

Zakir Khan ,Elouan Terrien ,Florent Delhommel ,Cynthia Lefebvre-Omar ,Delphine Bohl ,Sandrine Vitry ,Clara Bernard ,Juan Ramirez ,Alain Chaffotte ,Kevin Ricquier ,Renaud Vincentelli ,Henri Buc ,Christophe Prehaud ,Nicolas Wolff ,Monique Lafon

The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations

PARK2 基因敲除小鼠和 PARK2 突变患者的内质网-线粒体界面受到干扰

Clément A Gautier, Zoi Erpapazoglou, François Mouton-Liger, Marie Paule Muriel, Florence Cormier, Stéphanie Bigou, Sophie Duffaure, Mathilde Girard, Benjamin Foret, Angelo Iannielli, Vania Broccoli, Carine Dalle, Delphine Bohl, Patrick P Michel, Jean-Christophe Corvol, Alexis Brice, Olga Corti

Modeling amyotrophic lateral sclerosis in pure human iPSc-derived motor neurons isolated by a novel FACS double selection technique

通过新型 FACS 双选择技术分离纯人类 iPSc 衍生运动神经元,建立肌萎缩侧索硬化症模型

Diana Toli, Dorothée Buttigieg, Stéphane Blanchard, Thomas Lemonnier, Boris Lamotte d'Incamps, Sarah Bellouze, Gilbert Baillat, Delphine Bohl, Georg Haase

Neural progenitors derived from human induced pluripotent stem cells survive and differentiate upon transplantation into a rat model of amyotrophic lateral sclerosis

来自人类诱导性多能干细胞的神经祖细胞在移植到肌萎缩侧索硬化症大鼠模型后存活并分化

Iuliana Ristea Popescu, Charles Nicaise, Song Liu, Grégoire Bisch, Sarah Knippenberg, Valery Daubie, Delphine Bohl, Roland Pochet