日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The critical role of endoplasmic reticulum stress and the stimulator of interferon genes (STING) pathway in kidney fibrosis

内质网应激和干扰素基因刺激因子(STING)通路在肾纤维化中的关键作用

Andrade-Silva, Magaiver; Dhillon, Poonam; Sanchez-Navarro, Andrea; Mukhi, Dhanunjay; Hu, Hailong; Kolligundla, Lakshmi P; Bergeson, Andrea; Abedini, Amin; Levinsohn, Jonathan; Dumoulin, Bernhard; Câmara, Niels O S; Miner, Jonathan J; Susztak, Katalin

The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene.

肌动蛋白和微管网络调节因子 WHAMM 被确定为肾脏疾病的关键风险基因

Mukhi Dhanunjay, Kolligundla Lakshmi Prasanna, Doke Tomohito, Silva Magaiver Andrade-, Liu Hongbo, Palmer Matthew, Susztak Katalin

The key role of altered tubule cell lipid metabolism in kidney disease development

肾小管细胞脂质代谢改变在肾脏疾病发展中的关键作用

Lee, Lauren E; Doke, Tomohito; Mukhi, Dhanunjay; Susztak, Katalin

Hypoxia-Inducible Factor-2α Promotes Liver Fibrosis by Inducing Hepatocellular Death

缺氧诱导因子-2α诱导肝细胞死亡促进肝纤维化

Raja Gopal Reddy Mooli, Dhanunjay Mukhi, Mikayla Watt, Veerababu Nagati, Sara M Reed, Nikita K Gandhi, Michael Oertel, Sadeesh K Ramakrishnan

NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury

NAD+前体补充剂可预防肾损伤期间的mtRNA/RIG-I依赖性炎症

Tomohito Doke ,Sarmistha Mukherjee ,Dhanunjay Mukhi ,Poonam Dhillon ,Amin Abedini ,James G Davis ,Karthikeyani Chellappa ,Beishan Chen ,Joseph A Baur ,Katalin Susztak

Molecular pathways that drive diabetic kidney disease

驱动糖尿病肾病的分子通路

Mohandes, Samer; Doke, Tomohito; Hu, Hailong; Mukhi, Dhanunjay; Dhillon, Poonam; Susztak, Katalin

ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules

ACSS2基因变异通过控制肾小管中的从头脂肪生成来决定肾脏疾病风险。

Mukhi, Dhanunjay; Li, Lingzhi; Liu, Hongbo; Doke, Tomohito; Kolligundla, Lakshmi P; Ha, Eunji; Kloetzer, Konstantin; Abedini, Amin; Mukherjee, Sarmistha; Wu, Junnan; Dhillon, Poonam; Hu, Hailong; Guan, Dongyin; Funai, Katsuhiko; Uehara, Kahealani; Titchenell, Paul M; Baur, Joseph A; Wellen, Kathryn E; Susztak, Katalin

Metformin prevents hypoxia-induced podocyte injury by regulating the ZEB2/TG2 axis

二甲双胍通过调节 ZEB2/TG2 轴预防缺氧引起的足细胞损伤

Lakshmi P Kolligundla, Rajesh Kavvuri, Ashish K Singh, Dhanunjay Mukhi, Anil K Pasupulati

Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration

单细胞分析强调了适应性或纤维化肾脏再生的药物途径的差异

Michael S Balzer, Tomohito Doke, Ya-Wen Yang, Daniel L Aldridge, Hailong Hu, Hung Mai, Dhanunjay Mukhi, Ziyuan Ma, Rojesh Shrestha, Matthew B Palmer, Christopher A Hunter, Katalin Susztak

Intestinal HIF-2α Regulates GLP-1 Secretion via Lipid Sensing in L-Cells

肠道 HIF-2α 通过 L 细胞中的脂质感应调节 GLP-1 分泌

Raja Gopal Reddy Mooli, Dhanunjay Mukhi, Anil K Pasupulati, Simon S Evers, Ian J Sipula, Michael Jurczak, Randy J Seeley, Yatrik M Shah, Sadeesh K Ramakrishnan