日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Potent Inhibitor of Caspase‑8 Based on the IL-18 Tetrapeptide Sequence Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases.

基于 IL-18 四肽序列的强效 Caspase-8 抑制剂揭示了炎症和凋亡起始 Caspase 之间的共同特异性

Bourne Christopher M, Raniszewski Nicole R, Mahale Ashutosh B, Kulkarni Madhura, Exconde Patrick M, Liu Sherry, Yost Winslow, Wrong Tristan J, Patio Robert C, Kardhashi Matilda, Shosanya Teni, Kambayashi Mirai, Discher Bohdana M, Brodsky Igor E, Burslem George M, Taabazuing Cornelius Y

Human non-canonical inflammasomes activate CASP3 to limit intracellular Salmonella replication in macrophages.

人类非经典炎症小体激活 CASP3 以限制巨噬细胞内沙门氏菌的复制。

Kulkarni Madhura, Bourne Christopher M, Mahale Ashutosh B, Exconde Patrick M, Murphy Cecelia, Cervantes Sofia, Kardhashi Matilda, Kambayashi Mirai, Yoo William, Wrong Tristan J, Patio Robert C, Discher Bohdana M, Taabazuing Cornelius Y

Chemical Tools Based on the Tetrapeptide Sequence of IL-18 Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases.

基于IL-18四肽序列的化学工具揭示了炎症和凋亡起始半胱天冬酶之间的共同特异性

Bourne Christopher M, Raniszewski Nicole R, Kulkarni Madhura, Exconde Patrick M, Liu Sherry, Yost Winslow, Wrong Tristan J, Patio Robert C, Mahale Ashutosh, Kardhashi Matilda, Shosanya Teni, Kambayashi Mirai, Discher Bohdana M, Brodsky Igor E, Burslem George M, Taabazuing Cornelius Y

De novo protein design of photochemical reaction centers

光化学反应中心的从头蛋白质设计

Ennist, Nathan M; Zhao, Zhenyu; Stayrook, Steven E; Discher, Bohdana M; Dutton, P Leslie; Moser, Christopher C

Elementary tetrahelical protein design for diverse oxidoreductase functions

用于多种氧化还原酶功能的基本四螺旋蛋白设计

Farid, Tammer A; Kodali, Goutham; Solomon, Lee A; Lichtenstein, Bruce R; Sheehan, Molly M; Fry, Bryan A; Bialas, Chris; Ennist, Nathan M; Siedlecki, Jessica A; Zhao, Zhenyu; Stetz, Matthew A; Valentine, Kathleen G; Anderson, J L Ross; Wand, A Joshua; Discher, Bohdana M; Moser, Christopher C; Dutton, P Leslie

Design of amphiphilic protein maquettes: controlling assembly, membrane insertion, and cofactor interactions

两亲性蛋白模型的设计:控制组装、膜插入和辅因子相互作用

Discher, Bohdana M; Noy, Dror; Strzalka, Joseph; Ye, Shixin; Moser, Christopher C; Lear, James D; Blasie, J Kent; Dutton, P Leslie

Design of amphiphilic protein maquettes: enhancing maquette functionality through binding of extremely hydrophobic cofactors to lipophilic domains

两亲性蛋白模型的设计:通过将极疏水性辅因子与亲脂性结构域结合来增强模型的功能性

Noy, Dror; Discher, Bohdana M; Rubtsov, Igor V; Hochstrasser, Robin M; Dutton, P Leslie

Liquid-crystalline collapse of pulmonary surfactant monolayers

肺表面活性物质单层的液晶坍塌

Schief, William R; Antia, Meher; Discher, Bohdana M; Hall, Stephen B; Vogel, Viola