日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SNCA triplication disrupts proteostasis and extracellular architecture prior to neurodegeneration in human midbrain organoids.

SNCA 三倍体在人类中脑类器官发生神经退行性变之前会破坏蛋白质稳态和细胞外结构。

Statoulla Elpida, Zafeiri Maria, Chalkiadaki Kleanthi, Voudouri Georgia, Gkika Karmel S, Papazoglou Christos, Durcan Thomas M, Khoutorsky Arkady, Jafarnejad Seyed Mehdi, Maguire Sarah, Dityatev Alexander, Gkogkas Christos G

Activity-dependent extracellular proteolytic cascade cleaves the ECM component brevican to promote structural plasticity

活性依赖性细胞外蛋白水解级联反应切割细胞外基质成分brevican,从而促进结构可塑性

Singh, Jeet Bahadur; Perelló-Amorós, Bartomeu; Schneeberg, Jenny; Mirzapourdelavar, Hadi; Seidenbecher, Constanze I; Fejtová, Anna; Dityatev, Alexander; Frischknecht, Renato

High-Fat Diet and a High Amyloid Load Interact to Induce PKC-α Dependent Synaptic Insulin Resistance

高脂饮食和高淀粉样蛋白负荷相互作用诱导PKC-α依赖性突触胰岛素抵抗

Wenger, Alexander; Li, Tingting; Nguyen, Chi; Celik, Ali; Cuboni, Eleonora; Dityatev, Alexander; Karpova, Anna; Kreutz, Michael R; Ahrends, Robert

Vascular and Neural Transcriptomics Reveal Stage-Dependent Pathways to Inflammation and Cognitive Dysfunction in a Rat Model of Hypertension

血管和神经转录组学揭示高血压大鼠模型中炎症和认知功能障碍的阶段依赖性通路

Arndt, Philipp; Morton, Lorena; Briese, Michael; Lämmlin, Naomi; Mattern, Hendrik; Hasanuzzaman, Md; Westhues, Melina; Khoshneviszadeh, Mahsima; Appenzeller, Silke; Gündel, Daniel; Toussaint, Magali; Brust, Peter; Kniess, Torsten; Oelschlegel, Anja; Goldschmidt, Jürgen; Meuth, Sven; Müller, Patrick; Braun-Dullaeus, Rüdiger; Debska-Vielhaber, Grazyna; Vielhaber, Stefan; Becker, Axel; Dityatev, Alexander; Henneicke, Solveig; Sendtner, Michael; Dunay, Ildiko; Schreiber, Stefanie

Cerebellar Resistance to Amyloid Plaque Deposition and Elevated Microglial ECM Proteoglycan Uptake in 5xFAD Mice.

5xFAD 小鼠小脑对淀粉样斑块沉积的抵抗力和小胶质细胞 ECM 蛋白聚糖摄取增加。

Cangalaya Carla, Düsedau Henning Peter, Dunay Ildiko Rita, Dityatev Alexander, Stoyanov Stoyan

The Serine/Threonine Kinase NDR2 Regulates Integrin Signaling, Synapse Formation, and Synaptic Plasticity in the Hippocampus

丝氨酸/苏氨酸激酶NDR2调节海马体中的整合素信号传导、突触形成和突触可塑性

Miguel del Angel ,Atsuhiro Tsutiya ,Hussam Hayani ,Deniz Madencioglu ,Emre Kul ,Gürsel Caliskan ,Yunus Emre Demiray ,Alexander Dityatev ,Oliver Stork

Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice

补体蛋白C3介导的突触标记减少与中年小鼠小脑中细胞外基质增多有关。

Henning Peter Düsedau # ,Carla Cangalaya # ,Stoyan Stoyanov ,Alexander Dityatev ,Ildiko Rita Dunay

Focal clusters of peri-synaptic matrix contribute to activity-dependent plasticity and memory in mice

突触周围基质的焦点簇有助于小鼠的活动依赖性可塑性和记忆

Gabriele Chelini, Hadi Mirzapourdelavar, Peter Durning, David Baidoe-Ansah, Manveen K Sethi, Sinead M O'Donovan, Torsten Klengel, Luigi Balasco, Cristina Berciu, Anne Boyer-Boiteau, Robert McCullumsmith, Kerry J Ressler, Joseph Zaia, Yuri Bozzi, Alexander Dityatev, Sabina Berretta

Immune system activation and cognitive impairment in arterial hypertension

动脉高血压患者的免疫系统激活和认知功能障碍

Schreiber, Stefanie; Arndt, Philipp; Morton, Lorena; Garza, Alejandra P; Müller, Patrick; Neumann, Katja; Mattern, Hendrik; Dörner, Marc; Bernal, Jose; Vielhaber, Stefan; Meuth, Sven G; Dunay, Ildiko R; Dityatev, Alexander; Henneicke, Solveig

Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy

系统性炎症和 tau 蛋白病急性模型中小胶质细胞加剧突触重塑的实时机制

Carla Cangalaya, Susanne Wegmann, Weilun Sun, Lisa Diez, Anna Gottfried, Karin Richter, Stoyan Stoyanov, Janelle Pakan, Klaus-Dieter Fischer, Alexander Dityatev