日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Concurrent Inhibition of the RAS-MAPK Pathway and PIKfyve Is a Therapeutic Strategy for Pancreatic Cancer.

同时抑制 RAS-MAPK 通路和 PIKfyve 是胰腺癌的一种治疗策略

DeLiberty Jonathan M, Roach Mallory K, Stalnecker Clint A, Robb Ryan, Schechter Elyse G, Pieper Noah L, Taylor Khalilah E, Pita Lily M, Yang Runying, Bang Scott, Drizyte-Miller Kristina, Ackermann Sarah E, Nicewarner Peña Sheila R, Baldelli Elisa, Min Sophia M, Drewry David H, Petricoin Emanuel F 3rd, Morris John P 4th, Der Channing J, Cox Adrienne D, Bryant Kirsten L

Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy

对人类短尾蛋白DNA识别的结构性见解以及用于癌症治疗的新型结合剂的发现

Newman, Joseph A; Gavard, Angeline E; Imprachim, Nergis; Aitkenhead, Hazel; Sheppard, Hadley E; Te Poele, Robert; Clarke, Paul A; Hossain, Mohammad Anwar; Temme, Louisa; Oh, Hans J; Wells, Carrow I; Davis-Gilbert, Zachary W; Workman, Paul; Gileadi, Opher; Drewry, David H

Chemoproteomic Profiling of C. albicans for Characterization of Antifungal Kinase Inhibitors.

念珠菌化学蛋白质组学分析用于鉴定抗真菌激酶抑制剂

Shirley David J, Nandakumar Meganathan, Cabrera Aurora, Yiu Bonnie, Puumala Emily, Liu Zhongle, Robbins Nicole, Whitesell Luke, Smith Jeffrey L, Lyons Scott, Mordant Angie L, Herring Laura E, Graves Lee M, Couñago Rafael M, Drewry David H, Cowen Leah E, Willson Timothy M

A soft-stiff patterned bioengineering model reveals kinase pathways driving directional cell migration in pulmonary arterial hypertension.

软硬模式生物工程模型揭示了驱动肺动脉高压中定向细胞迁移的激酶通路

Islam Tamanna, Hooper Jacob, Zhang Xiaojun, Garcia Clarissa, Hasan Md Mahedi, Drewry David H, Hossain Mohammad Anwar, Al-Hilal Taslim A

NEK Family Kinases: Structure, Function, and Role in Disease

NEK家族激酶:结构、功能及其在疾病中的作用

Baker, Brandon M; Boehling, Julia R; Knopf, Sarah; Held, Stephanie; Matossian, Margarite; Belgodere, Jorge A; Hoang, Van T; Collins-Burow, Bridgette M; Martin, Elizabeth C; Lee, Sean B; Burow, Matthew E; Drewry, David H; Newman, Robert H

NUAK kinases: Signaling mechanisms and therapeutic applications

NUAK激酶:信号传导机制和治疗应用

Cullen, Nicole M; Rosston, Peter; Tufail, Bakhtawar; D'Armond, Anne E; Patel, Ayushi; Khosravi, Dara H; Collins-Burow, Bridgette M; Hoang, Van T; Martin, Elizabeth C; Drewry, David H; Burow, Matthew E; Alahari, Suresh K

Chemoproteomic Profiling of C. albicans for Characterization of Anti-fungal Kinase Inhibitors

利用化学蛋白质组学分析白色念珠菌,以鉴定抗真菌激酶抑制剂

Shirley, David J; Nandakumar, Meganathan; Cabrera, Aurora; Yiu, Bonnie; Puumala, Emily; Liu, Zhongle; Robbins, Nicole; Whitesell, Luke; Smith, Jeffrey L; Lyons, Scott P; Mordant, Angie L; Herring, Laura E; Graves, Lee M; Couñago, Rafael M; Drewry, David H; Cowen, Leah E; Willson, Timothy M

Cellular Selectivity Analyses Reveal Distinguishing Profiles for Type II Kinase Inhibitors

细胞选择性分析揭示了II型激酶抑制剂的独特特征

Binder, Matthew J; Bashore, Frances M; Hoffman, Kaitlin K Dunn; Daamgard, Cameron; Slater, Michael R; Drewry, David H; Robers, Matthew B; Axtman, Alison D

NUAK2 is a therapeutically tractable regulator of RNA splicing and tumor progression in neuroendocrine prostate cancer

NUAK2是神经内分泌前列腺癌中RNA剪接和肿瘤进展的一个具有治疗潜力的调节因子。

Mehraj, Umar; Maimekov, Uran; Manzoor, Shaista; Cordova, Emily; Patel, Manasiben; Mancera-Ortiz, Ikeer Y; Howell, Stefanie; Davis-Gilbert, Zachary W; Wang, Mu-En; Chen, Ming; Park, Jung Wook; Wang, Yuzhuo; Armstrong, Andrew J; Huang, Jiaoti; Drewry, David H; Mitrofanova, Antonina; Macias, Everardo

Structure-activity Relationship for Diarylpyrazoles as Inhibitors of the Fungal Kinase Yck2.

二芳基吡唑类化合物作为真菌激酶Yck2抑制剂的构效关系

Shirley David J, Yiu Bonnie, Mancera-Ortiz Ikeer, Stogios Peter J, Liu Zhongle, Robbins Nicole, Whitesell Luke, Cowen Leah E, Drewry David H, Willson Timothy M