日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Scale-up of a monoclonal antibody CHO fed-batch production in stirred tank bioreactors: Effect of hydrodynamic conditions and feeding regimen

在搅拌罐式生物反应器中，采用CHO补料分批法放大单克隆抗体的生产：流体动力学条件和补料方案的影响

期刊:Biotechnology Progress
影响因子:2.5
doi:10.1002/btpr.70073
Lemire, Lucas; Reyes, Sebastian-Juan; Durocher, Yves; Voyer, Robert; Henry, Olivier; Pham, Phuong Lan
单克隆抗体
发表日期：2026
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Erratum: Lipid nanoparticle encapsulation of a Delta spike-CD40L DNA vaccine improves effectiveness against Omicron challenge in Syrian hamsters

更正：脂质纳米颗粒包裹的Delta刺突蛋白-CD40L DNA疫苗提高了对叙利亚仓鼠Omicron攻击的有效性

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1016/j.omtm.2024.101388
Tamming, Levi; Duque, Diana; Tran, Anh; Lansdell, Casey; Frahm, Grant; Wu, Jianguo; Fekete, Emily E F; Creskey, Marybeth; Thulasi Raman, Sathya N; Laryea, Emmanuel; Zhang, Wanyue; Pfeifle, Annabelle; Gravel, Caroline; Stalker, Andrew; Hashem, Anwar M; Chen, Wangxue; Stuible, Matthew; Durocher, Yves; Safronetz, David; Cao, Jingxin; Wang, Lisheng; Sauve, Simon; Rosu-Myles, Michael; Zhang, Xu; Johnston, Michael J W; Li, Xuguang
T细胞
CD4
CD40
发表日期：2025
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Use of Coiled-Coil Affinity Peptides to Manufacture Antibody Conjugates

利用卷曲螺旋亲和肽制备抗体偶联物

期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.5c00178
Baniahmad, Seyed Farzad; Burlacu, Alina; Delafosse, Laurence; Acchione, Mauro; Simmons, Miriam; Ling, Binbing; Iqbal, Umar; Moreno, Maria J; De Crescenzo, Gregory; Durocher, Yves
发表日期：2025
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Endogenous Retrovirus-Like Particle-Deficient CHO Cells Can be Generated by CRISPR or shRNA and Enriched Based on Cell-Surface Expression of Retroviral Envelope Protein

利用 CRISPR 或 shRNA 技术可以构建缺乏内源性逆转录病毒样颗粒的 CHO 细胞，并基于逆转录病毒包膜蛋白的细胞表面表达进行富集。

期刊:Biotechnology and Bioengineering
影响因子:3.6
doi:10.1002/bit.70043
Stuible, Matthew; Alpuche-Lazcano, Sergio P; Gervais, Christian; Ouimet, Manon; Lippens, Julie; Pagé, Martine; Morasse, Audrey; Moraitis, Anna N; Durocher, Yves
微生物学
细胞生物学
发表日期：2025
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A Surface Plasmon Resonance-Based Integrated Assay for Quantification and Glycosylation Characterization of Monoclonal Antibodies in Crude Heterogeneous Samples.

基于表面等离子体共振的综合检测方法，用于对粗制异质样品中的单克隆抗体进行定量和糖基化表征

期刊:Biotechnology and Bioengineering
影响因子:3.6
doi:10.1002/bit.70016
Metayer Ilona, Forest-Nault Catherine, Guimond Julie, Joubert Simon, Henry Olivier, Durocher Yves, De Crescenzo Gregory, Gaudreault Jimmy
免疫/内分泌
发表日期：2025
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Optimized Production of Virus-like Particles in a High-CHO-Cell-Density Transient Gene Expression System for Foot-and-Mouth Disease Vaccine Development

利用高密度CHO细胞瞬时基因表达系统优化病毒样颗粒的生产，用于口蹄疫疫苗的研发

期刊:Vaccines
影响因子:3.4
doi:10.3390/vaccines13060581
Mignaqui, Ana Clara; Ferella, Alejandra; Sánchez, Cintia; Stuible, Matthew; Scian, Romina; Filippi, Jorge; Cardillo, Sabrina Beatriz; Durocher, Yves; Wigdorovitz, Andrés
微生物学
细胞生物学
发表日期：2025
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Immunogenicity of Sulfated Lactosyl Archaeol Archaeosome-Adjuvanted Versus Non-Adjuvanted SARS-CoV-2 Spike Booster Vaccines in Young and Aged Balb/c Mice

在年轻和年老的Balb/c小鼠中，硫酸乳糖基古菌醇佐剂与非佐剂SARS-CoV-2刺突蛋白加强疫苗的免疫原性比较

期刊:Vaccines
影响因子:3.4
doi:10.3390/vaccines13121257
Stark, Felicity C; Akache, Bassel; Renner, Tyler M; Agbayani, Gerard; Deschatelets, Lise; Dudani, Renu; Harrison, Blair A; Hemraz, Usha D; Régnier, Sophie; Stuible, Matthew; Durocher, Yves; McCluskie, Michael J
SARS-CoV-2
免疫/内分泌
发表日期：2025
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N-1 semi-continuous transient perfusion in shake flask for ultra-high density seeding of CHO cell cultures in benchtop bioreactors

N-1 半连续瞬态灌注法在摇瓶中进行超高密度 CHO 细胞培养接种，适用于台式生物反应器

期刊:Biotechnology Progress
影响因子:2.5
doi:10.1002/btpr.70029
Lemire, Lucas; Reyes, Sebastian-Juan; Durocher, Yves; Voyer, Robert; Henry, Olivier; Pham, Phuong Lan
Cell Culture
细胞生物学
发表日期：2025
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A recurrent neural network for soft sensor development using CHO stable pools in fed-batch process for SARS-CoV-2 spike protein production as a vaccine antigen

一种用于软传感器开发的循环神经网络，利用CHO稳定细胞池在补料分批培养工艺中生产SARS-CoV-2刺突蛋白（作为疫苗抗原）

期刊:Biotechnology Progress
影响因子:2.5
doi:10.1002/btpr.70046
Reyes, Sebastian-Juan; Voyer, Robert; Durocher, Yves; Henry, Olivier; Pham, Phuong Lan
SARS-CoV-2
细胞生物学
发表日期：2025
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SARS-CoV-2 conjugate vaccine elicits robust immune responses that can protect against evolving variants

SARS-CoV-2 结合疫苗可引发强烈的免疫反应，从而抵御不断演变的变异株。

期刊:
影响因子:
doi:10.1016/j.vaccine.2025.126988
Carroll, Melanie; Fox, Heather B; Tran, Anh; Chellappan, Gowri; Rojas, Leonardo V; Karengil, Geetha; Karandish, Fataneh; Langston, John W; Fall, Brent M; Whalen, Mary M; McCluskie, Michael J; Durocher, Yves; Datta, Anup; Kapre, Subhash V; Olave, Ivan A
SARS-CoV-2
免疫/内分泌
发表日期：2025
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