日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Diminished gallbladder filling, increased fecal bile acids, and promotion of colon epithelial cell proliferation and neoplasia in fibroblast growth factor 15-deficient mice

成纤维细胞生长因子 15 缺乏的小鼠胆囊充盈减少、粪便胆汁酸增加、结肠上皮细胞增殖和肿瘤形成促进

Kunrong Cheng, Melissa Metry, Jessica Felton, Aaron C Shang, Cinthia B Drachenberg, Su Xu, Min Zhan, Justin Schumacher, Grace L Guo, James E Polli, Jean-Pierre Raufman

A substrate pharmacophore for the human sodium taurocholate co-transporting polypeptide

人类牛磺胆酸钠共转运多肽的底物药效团

Zhongqi Dong, Sean Ekins, James E Polli

Quantitative NTCP pharmacophore and lack of association between DILI and NTCP Inhibition

定量 NTCP 药效团以及 DILI 与 NTCP 抑制之间缺乏关联

Zhongqi Dong, Sean Ekins, James E Polli

Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids

Slc10a2 基因敲除小鼠揭示内源性粪便胆汁酸促进结肠癌的作用

Jean-Pierre Raufman, Paul A Dawson, Anuradha Rao, Cinthia B Drachenberg, Jonathon Heath, Aaron C Shang, Shien Hu, Min Zhan, James E Polli, Kunrong Cheng

The role of bile salt export pump gene repression in drug-induced cholestatic liver toxicity

胆汁盐输出泵基因抑制在药物引起的胆汁淤积性肝毒性中的作用

Brandy Garzel, Hui Yang, Lei Zhang, Shiew-Mei Huang, James E Polli, Hongbing Wang

Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs)

昂丹司琼可通过抑制多种毒素和挤出蛋白 (MATE) 增强顺铂诱导的肾毒性

Qing Li, Dong Guo, Zhongqi Dong, Wei Zhang, Lei Zhang, Shiew-Mei Huang, James E Polli, Yan Shu

Structure-activity relationship for FDA approved drugs as inhibitors of the human sodium taurocholate cotransporting polypeptide (NTCP)

FDA 批准的人类牛磺胆酸钠转运多肽 (NTCP) 抑制剂药物的构效关系

Zhongqi Dong, Sean Ekins, James E Polli

Noninvasive near-infrared live imaging of human adult mesenchymal stem cells transplanted in a rodent model of Parkinson's disease

对移植到帕金森病啮齿动物模型中的人类成人间充质干细胞进行无创近红外活体成像

P Bossolasco, L Cova, G Levandis, V Diana, S Cerri, G Lambertenghi Deliliers, E Polli, V Silani, F Blandini, M T Armentero

Transmembrane helix 1 contributes to substrate translocation and protein stability of bile acid transporter SLC10A2

跨膜螺旋 1 有助于胆汁酸转运蛋白 SLC10A2 的底物转运和蛋白质稳定性

Tatiana Claro da Silva, Naissan Hussainzada, Chandra M Khantwal, James E Polli, Peter W Swaan

Impact of impurity on kinetic estimates from transport and inhibition studies

杂质对运输和抑制研究中动力学估计的影响

Pablo González, James E Polli