日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer.

释放利戈塞替尼作为卵巢癌选择性疗法的治疗潜力

Nath Shalini, Claridge Sally, Granados Genesis Lara, Al Assaad Majd, Park Eric, Cavallo Julie-Ann, Nuwere Ufuoma, Ackon Maame Esi, De Boni Lamberto, Baker Stacey, Reddy E Premkumar, Blank Stephanie V, Elemento Olivier, Brody Rachel, Hopkins Benjamin D

A Drosophila model for Costello Syndrome caused by Ras mutation K117R

由 Ras 基因 K117R 突变引起的 Costello 综合征的果蝇模型

Karunaraj, Prashath; Cao, Emily; Singh, Harnoor; Luf, Max; Baker, Stacey J; Reddy, E Premkumar; Pfleger, Cathie M

Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate Cancer

主转录因子重编程释放选择性翻译,促进致命前列腺癌的去势抵抗和免疫逃避

Sandra Santasusagna #, Shijia Zhu #, Vijayakumar Jawalagatti #, Marc Carceles-Cordon, Adam Ertel, Saioa Garcia-Longarte, Won-Min Song, Naoto Fujiwara, Peiyao Li, Isabel Mendizabal, Daniel P Petrylak, William Kevin Kelly, E Premkumar Reddy, Liguo Wang, Matthew J Schiewer, Amaia Lujambio, Jeffrey Karn

TGFβ reprograms TNF stimulation of macrophages towards a non-canonical pathway driving inflammatory osteoclastogenesis

TGFβ 重新编程 TNF 对巨噬细胞的刺激,使其转向驱动炎症破骨细胞生成的非经典通路

Yuhan Xia #, Kazuki Inoue #, Yong Du, Stacey J Baker, E Premkumar Reddy, Matthew B Greenblatt, Baohong Zhao

A prospective study of asymptomatic SARS-CoV-2 infection among individuals involved in academic research under limited operations during the COVID-19 pandemic

一项针对COVID-19疫情期间受限运营环境下从事学术研究人员的无症状SARS-CoV-2感染的前瞻性研究

Pettifor, Audrey; DiPrete, Bethany L; Shook-Sa, Bonnie E; Premkumar, Lakshmanane; Kuczynski, Kriste; Dittmer, Dirk; Aiello, Allison; Wallet, Shannon; Maile, Robert; Tan, Joyce; Jadi, Ramesh; Pluta, Linda; de Silva, Aravinda M; Weber, David J; Kim, Min; Seña, Arlene C; Jones, Corbin D

CDK4: a master regulator of the cell cycle and its role in cancer

CDK4:细胞周期的主要调控因子及其在癌症中的作用

Baker, Stacey J; Poulikakos, Poulikos I; Irie, Hanna Y; Parekh, Samir; Reddy, E Premkumar

Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade

通过抑制 RAS/RAF/PI3K 通路,肿瘤细胞可新诱导 CD40 表达,从而增强对检查点阻断的反应

Chi Yan, Nabil Saleh, Jinming Yang, Caroline A Nebhan, Anna E Vilgelm, E Premkumar Reddy, Joseph T Roland, Douglas B Johnson, Sheau-Chiann Chen, Rebecca L Shattuck-Brandt, Gregory D Ayers, Ann Richmond

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease

108600 同时抑制 CK2/TNIK/DYRK1 可抑制三阴性乳腺癌干细胞和化疗耐药性疾病

Katsutoshi Sato #, Amol A Padgaonkar #, Stacey J Baker, Stephen C Cosenza, Olga Rechkoblit, D R C Venkata Subbaiah, Josep Domingo-Domenech, Alison Bartkowski, Elisa R Port, Aneel K Aggarwal, M V Ramana Reddy, Hanna Y Irie, E Premkumar Reddy

Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression

Posiphen 通过抑制翻译来降低亨廷顿蛋白的水平

Xu-Qiao Chen, Carlos A Barrero, Rodrigo Vasquez-Del Carpio, E Premkumar Reddy, Chiara Fecchio, Salim Merali, Alessia Deglincerti, Cheng Fang, Jack Rogers, Maria L Maccecchini

A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding Agent

污染杂质(而非 Rigosertib)是一种微管蛋白结合剂

Stacey J Baker, Stephen C Cosenza, Saikrishna Athuluri-Divakar, M V Ramana Reddy, Rodrigo Vasquez-Del Carpio, Rinku Jain, Aneel K Aggarwal, E Premkumar Reddy