日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A robust protocol to map binding sites of the 14-3-3 interactome: Cdc25C requires phosphorylation of both S216 and S263 to bind 14-3-3

绘制 14-3-3 相互作用组结合位点的稳健方案:Cdc25C 需要 S216 和 S263 均磷酸化才能结合 14-3-3

Perry M Chan, Yuen-Wai Ng, Ed Manser

PAK5 is auto-activated by a central domain that promotes kinase oligomerization

PAK5 由促进激酶寡聚化的中心域自动激活

Bahareh Tabanifar, Zhuoshen Zhao, Ed Manser

Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network

Formin DAAM1 在细胞质节点肌动蛋白网络中组织肌动蛋白丝

Weiwei Luo, Zi Zhao Lieu, Ed Manser, Alexander D Bershadsky, Michael P Sheetz

An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1

PAK4 与其抑制剂 Inka1 复合的细胞内衍生结构

Yohendran Baskaran, Khay C Ang, Praju V Anekal, Wee L Chan, Jonathan M Grimes, Ed Manser, Robert C Robinson

Arg kinase-binding protein 2 (ArgBP2) interaction with α-actinin and actin stress fibers inhibits cell migration

Arg激酶结合蛋白2(ArgBP2)与α-肌动蛋白和肌动蛋白应力纤维相互作用抑制细胞迁移

Praju Vikas Anekal, Jeffery Yong, Ed Manser

The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity

Cdc42 效应激酶 PAK4 定位于细胞间连接处并有助于建立细胞极性

Widyawilis Selamat, Pei-Ling Felicia Tay, Yohendran Baskaran, Ed Manser

The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation

PAK 系统将 Rho GTPase 信号与凝血酶介导的血小板活化联系起来

Joseph E Aslan, Sandra M Baker, Cassandra P Loren, Kristina M Haley, Asako Itakura, Jiaqing Pang, Daniel L Greenberg, Larry L David, Ed Manser, Jonathan Chernoff, Owen J T McCarty

Group I and II mammalian PAKs have different modes of activation by Cdc42

组和 II 组哺乳动物 PAK 被 Cdc42 激活的方式不同

Yohendran Baskaran, Yuen-Wai Ng, Widyawilis Selamat, Felicia Tay Pei Ling, Ed Manser

Collapsin response mediator proteins (CRMPs) are a new class of microtubule-associated protein (MAP) that selectively interacts with assembled microtubules via a taxol-sensitive binding interaction

Collapsin 反应介导蛋白 (CRMP) 是一类新型微管相关蛋白 (MAP),可通过紫杉醇敏感的结合相互作用选择性地与组装的微管相互作用

Pao-Chun Lin, Perry M Chan, Christine Hall, Ed Manser

Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling

细胞质 ACK1 与多种受体酪氨酸激酶的相互作用由 Grb2 介导:ACK1 对 Axl 信号传导影响的分析

Lin Pao-Chun, Perry M Chan, Wing Chan, Ed Manser