日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Evidence human FTO catalyses hydroxylation of N6-methyladenosine without direct formation of a demethylated product contrasting with ALKBH5/2/3 and bacterial AlkB

证据表明，人类FTO催化N6-甲基腺苷的羟基化，而不会直接生成去甲基化产物，这与ALKBH5/2/3和细菌AlkB形成对比。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf813
Kaur, Simranjeet; Maheswaran, Pratheesh; Kaur, Samanpreet; Lai, Yingqi; Salah, Eidarus; Zhang, Dong; Shishodia, Shifali; Schofield, Christopher J; Aik, Wei Shen
微生物学
ALK
表观遗传
发表日期：2025
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Derivatives of the Clinically Used HIF Prolyl Hydroxylase Inhibitor Desidustat Are Efficient Inhibitors of Human γ-Butyrobetaine Hydroxylase

临床使用的HIF脯氨酰羟化酶抑制剂Desidustat的衍生物是人γ-丁酰甜菜碱羟化酶的有效抑制剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00586
Corner, Thomas P; Tumber, Anthony; Salah, Eidarus; Jabbary, Mohammadparsa; Nakashima, Yu; Schnaubelt, Lara I; Basak, Shyam; Alshref, Faisal M; Brewitz, Lennart; Schofield, Christopher J
Human
发表日期：2025
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Profiling Inhibitor Scaffolds for the Cancer Target Jumonji-C Domain-Containing Protein 6

针对癌症靶点 Jumonji-C 结构域蛋白 6 的抑制剂支架分析

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.202500682
Corner, Thomas P; Salah, Eidarus; Tumber, Anthony; Holt-Martyn, James P; Brewitz, Lennart; Schofield, Christopher J
肿瘤
肿瘤免疫
发表日期：2025
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RaPID discovery of cell-permeable helical peptide inhibitors con-taining cyclic β-amino acids against SARS-CoV-2 main protease

快速发现含有环状β-氨基酸的细胞渗透性螺旋肽抑制剂，该抑制剂可抑制SARS-CoV-2主蛋白酶

期刊:RSC Chemical Biology
影响因子:3.1
doi:10.1039/d5cb00021a
Kawai, Marina; Malla, Tika R; Chan, H T Henry; Tumber, Anthony; Brewitz, Lennart; Salah, Eidarus; Terasaka, Naohiro; Katoh, Takayuki; Kawamura, Akane; Schofield, Christopher J; Duarte, Fernanda; Suga, Hiroaki
SARS-CoV-2
细胞生物学
发表日期：2025
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Biochemical investigations using mass spectrometry to monitor JMJD6-catalysed hydroxylation of multi-lysine containing bromodomain-derived substrates

利用质谱法监测JMJD6催化的多赖氨酸溴结构域衍生底物的羟基化反应的生化研究

期刊:RSC Chemical Biology
影响因子:3.1
doi:10.1039/d4cb00311j
Corner, Thomas P; Salah, Eidarus; Tumber, Anthony; Brewitz, Lennart; Schofield, Christopher J
JMJD6
发表日期：2025
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Investigating the N-terminal linker histone H1 subtypes as substrates for JmjC lysine demethylases.

研究 N 端连接组蛋白 H1 亚型作为 JmjC 赖氨酸去甲基酶的底物

期刊:RSC Chemical Biology
影响因子:3.1
doi:10.1039/d5cb00083a
Türkmen Vildan A, Tumber Anthony, Salah Eidarus, Kaur Samanpreet, Schofield Christopher J, Mecinović Jasmin
免疫/内分泌
发表日期：2025
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The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia

选择性脯氨酰羟化酶抑制剂 IOX5 可稳定 HIF-1α 并抑制急性髓系白血病的发展和进展

期刊:Nature Cancer
影响因子:23.5
doi:10.1038/s43018-024-00761-w
Hannah Lawson #, James P Holt-Martyn #, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew Bowen, Louis Dubusse, 
肿瘤
白血病
发表日期：2024
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Thiophene-fused γ-lactams inhibit the SARS-CoV-2 main protease via reversible covalent acylation

噻吩稠合的γ-内酰胺类化合物通过可逆共价酰化作用抑制SARS-CoV-2主蛋白酶。

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d4sc01027b
Gayatri; Brewitz, Lennart; Ibbotson, Lewis; Salah, Eidarus; Basak, Shyam; Choudhry, Hani; Schofield, Christopher J
SARS-CoV-2
发表日期：2024
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Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate

重点筛选确定人类 TET 加氧酶对癌代谢物 2-羟基戊二酸的不同敏感性

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.3c01820
Roman Belle, Hilal Saraç, Eidarus Salah, Bhaskar Bhushan, Aleksandra Szykowska, Grace Roper, Anthony Tumber, Skirmantas Kriaucionis, Nicola Burgess-Brown, Christopher J Schofield, Tom Brown, Akane Kawamura
代谢
肿瘤
HTRF
Human
发表日期：2024
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Substrate selectivity and inhibition of the human lysyl hydroxylase JMJD7

人赖氨酰羟化酶JMJD7的底物选择性和抑制作用

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.5162
Bilgin, Nurgül; Tumber, Anthony; Dhingra, Siddhant; Salah, Eidarus; Al-Salmy, Aziza; Martín, Sandra Pinzón; Wang, Yicheng; Schofield, Christopher J; Mecinović, Jasmin
发表日期：2024
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