日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Shigella OspF blocks rapid p38-dependent priming of the NAIP-NLRC4 inflammasome

志贺氏菌OspF阻断p38依赖的NAIP-NLRC4炎症小体的快速启动

Turcotte, Elizabeth A; Kim, Kyungsub; Eislmayr, Kevin D; Goers, Lisa; Mitchell, Patrick S; Lesser, Cammie F; Vance, Russell E

Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

巨噬细胞通过TLR诱导的IL-12和IFN-γ介导的清除作用,将志贺氏菌从肠道上皮细胞微环境中清除。

Kevin D Eislmayr ,Charlotte A Nichols ,Fitty L Liu ,Sudyut Yuvaraj ,Janet Peace Babirye ,Justin L Roncaioli ,Jenna Vickery ,Gregory M Barton ,Cammie F Lesser ,Russell E Vance

Shigella OspF blocks rapid p38-dependent priming of the NAIP-NLRC4 inflammasome.

志贺氏菌 OspF 阻断 NAIP-NLRC4 炎症小体的 p38 依赖性快速启动

Turcotte Elizabeth A, Kim Kyungsub, Eislmayr Kevin D, Goers Lisa, Mitchell Patrick S, Lesser Cammie F, Vance Russell E

Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection

IL-1α 和 IL-1β 的非冗余性体现在它们对组织的不同调控作用上,这些调控作用决定了组织对感染的抵抗力和耐受性。

Kevin Eislmayr ,Annika Bestehorn ,Luisa Morelli ,Martina Borroni ,Lieselotte Vande Walle ,Mohamed Lamkanfi ,Pavel Kovarik

Impaired Mucosal Homeostasis in Short-Term Fiber Deprivation Is Due to Reduced Mucus Production Rather Than Overgrowth of Mucus-Degrading Bacteria

短期纤维缺乏导致的黏膜稳态受损是由于黏液分泌减少而非黏液降解细菌过度生长所致。

Overbeeke, Annelieke; Lang, Michaela; Hausmann, Bela; Watzka, Margarete; Nikolov, Georgi; Schwarz, Jasmin; Kohl, Gudrun; De Paepe, Kim; Eislmayr, Kevin; Decker, Thomas; Richter, Andreas; Berry, David

The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains

泛素连接酶HOIL-1L通过与线性泛素链相互作用来调节免疫反应。

Carlos Gomez-Diaz ,Gustav Jonsson ,Katrin Schodl ,Luiza Deszcz ,Annika Bestehorn ,Kevin Eislmayr ,Jorge Almagro ,Anoop Kavirayani ,Mayu Seida ,Lilian M Fennell ,Astrid Hagelkruys ,Pavel Kovarik ,Josef M Penninger ,Fumiyo Ikeda

Context-Dependent IL-1 mRNA-Destabilization by TTP Prevents Dysregulation of Immune Homeostasis Under Steady State Conditions

TTP 引起的依赖于环境的 IL-1 mRNA 不稳定可防止稳定状态下免疫稳态失调

Lucy Sneezum, Kevin Eislmayr, Helene Dworak, Vitaly Sedlyarov, Anita Le Heron, Florian Ebner, Irmgard Fischer, Yoichiro Iwakura, Pavel Kovarik

Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions

IFN-γ 的转录反应需要介导激酶依赖的暂停释放以及机制不同的 CDK8 和 CDK19 功能

Iris Steinparzer ,Vitaly Sedlyarov ,Jonathan D Rubin ,Kevin Eislmayr ,Matthew D Galbraith ,Cecilia B Levandowski ,Terezia Vcelkova ,Lucy Sneezum ,Florian Wascher ,Fabian Amman ,Renata Kleinova ,Heather Bender ,Zdenek Andrysik ,Joaquin M Espinosa ,Giulio Superti-Furga ,Robin D Dowell ,Dylan J Taatjes ,Pavel Kovarik