日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Direct effects of adipocyte lipolysis on AMPK through intracellular long-chain acyl-CoA signaling

脂肪细胞脂肪分解通过细胞内长链酰基辅酶 A 信号对 AMPK 的直接影响

Abir A Rahman, Andrew J Butcko, Emmanuel Songyekutu, James G Granneman, Emilio P Mottillo

Lipid droplet targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis

ABHD5 和 PNPLA3 I148M 脂滴靶向作用是促进肝脏脂肪变性所必需的

Grace Teskey, Nivedita Tiwari, Andrew J Butcko, Amit Kumar, Anu Yadav, Yuming M Huang, Christopher V Kelly, James G Granneman, James W Perfield, Emilio P Mottillo

A FRET sensor for the real-time detection of long chain acyl-CoAs and synthetic ABHD5 ligands

用于实时检测长链酰基辅酶 A 和合成 ABHD5 配体的 FRET 传感器

Emilio P Mottillo, Ljiljana Mladenovic-Lucas, Huamei Zhang, Li Zhou, Christopher V Kelly, Pablo A Ortiz, James G Granneman

Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes

ABHD5 与 PNPLA3 的动态相互作用调节棕色脂肪细胞中的三酰甘油代谢

Alexander Yang, Emilio P Mottillo, Ljiljana Mladenovic-Lucas, Li Zhou, James G Granneman

FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis

FGF21 不需要脂肪细胞 AMP 活化蛋白激酶 (AMPK) 或乙酰辅酶 A 羧化酶 (ACC) 的磷酸化来介导全身葡萄糖稳态的改善

Emilio P Mottillo, Eric M Desjardins, Andreas M Fritzen, Vito Z Zou, Justin D Crane, Julian M Yabut, Bente Kiens, Derek M Erion, Adhiraj Lanba, James G Granneman, Saswata Talukdar, Gregory R Steinberg

Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1

水杨酸酯(水杨酸盐)可分离线粒体、改善葡萄糖稳态并降低肝脏脂质,且不依赖于 AMPK-β1

Brennan K Smith, Rebecca J Ford, Eric M Desjardins, Alex E Green, Meghan C Hughes, Vanessa P Houde, Emily A Day, Katarina Marcinko, Justin D Crane, Emilio P Mottillo, Christopher G R Perry, Bruce E Kemp, Mark A Tarnopolsky, Gregory R Steinberg

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

抑制外周血清素合成可通过促进棕色脂肪组织产热来减少肥胖和代谢功能障碍

Justin D Crane, Rengasamy Palanivel, Emilio P Mottillo, Adam L Bujak, Huaqing Wang, Rebecca J Ford, Andrew Collins, Regje M Blümer, Morgan D Fullerton, Julian M Yabut, Janice J Kim, Jean-Eric Ghia, Shereen M Hamza, Katherine M Morrison, Jonathan D Schertzer, Jason R B Dyck, Waliul I Khan, Gregory R

Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation

慢性 β3-肾上腺素受体激活过程中棕色、米色和白色脂肪组织中的脂肪分解和从头脂肪生成的偶联

Emilio P Mottillo, Priya Balasubramanian, Yun-Hee Lee, Changren Weng, Erin E Kershaw, James G Granneman

Inducible brown adipocytes in subcutaneous inguinal white fat: the role of continuous sympathetic stimulation

皮下腹股沟白色脂肪中可诱导的棕色脂肪细胞:持续交感神经刺激的作用

G Andres Contreras, Yun-Hee Lee, Emilio P Mottillo, James G Granneman

Adipocyte lipolysis-stimulated interleukin-6 production requires sphingosine kinase 1 activity

脂肪细胞脂肪分解刺激白细胞介素-6的产生需要鞘氨醇激酶1活性

Wenliang Zhang, Emilio P Mottillo, Jiawei Zhao, Allison Gartung, Garrett C VanHecke, Jen-Fu Lee, Krishna R Maddipati, Haiyan Xu, Young-Hoon Ahn, Richard L Proia, James G Granneman, Menq-Jer Lee