日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EGFR amplification and PI3K pathway mutations identify a subset of breast cancers that synergistically respond to EGFR and PI3K inhibition

EGFR扩增和PI3K通路突变可识别出一部分对EGFR和PI3K抑制剂具有协同反应的乳腺癌亚群。

David J Wisniewski,Donna Voeller,Yonit A Addissie,Sachin Kumar Deshmukh,Sharon Wu,Maryam B Lustberg,Darawalee Wangsa,Danny Wangsa,Kerstin Heselmeyer-Haddad,Yoshimi Endo Greer,George W Sledge,Stanley Lipkowitz

Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer

通过联合使用NAMPT抑制剂和双硫仑来靶向代谢脆弱性,治疗复发性卵巢癌

Kei Kudo ,Yoshimi Endo Greer ,Daniel R Crooks ,Ye Yang ,Jeffrey R Brender ,Teruhiko Yoshida ,Brittney S Harrington ,Rahul Kamdar ,Soumya Korrapati ,Yusuke Shibuya ,Leah Henegar ,Jeffrey Kopp ,Takeo Fujii ,Stanley Lipkowitz ,Christina M Annunziata

Dual-inhibition of NAMPT and PAK4 induces anti-tumor effects in 3D-spheroids model of platinum-resistant ovarian cancer

双重抑制NAMPT和PAK4可在铂耐药卵巢癌的3D球体模型中诱导抗肿瘤作用

Kei Kudo ,Yoshimi Endo Greer ,Teruhiko Yoshida ,Brittney S Harrington ,Soumya Korrapati ,Yusuke Shibuya ,Leah Henegar ,Jeffrey B Kopp ,Takeo Fujii ,Stanley Lipkowitz ,Christina M Annunziata

Characterization of TR-107, a novel chemical activator of the human mitochondrial protease ClpP

TR-107 的特性分析:一种新型的人类线粒体蛋白酶 ClpP 化学激活剂

Emily M J Fennell ,Lucas J Aponte-Collazo ,Joshua D Wynn ,Kristina Drizyte-Miller ,Elisa Leung ,Yoshimi Endo Greer ,Paul R Graves ,Andrew A Iwanowicz ,Hani Ashamalla ,Ekhson Holmuhamedov ,Henk Lang ,Donald S Karanewsky ,Channing J Der ,Walid A Houry ,Stanley Lipkowitz ,Edwin J Iwanowicz ,Lee M Graves

MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer

MEDI3039 是一种新型高效肿瘤坏死因子 (TNF) 相关凋亡诱导配体 (TRAIL) 受体 2 激动剂,可导致原位肿瘤消退并抑制转移性三阴性乳腺癌的生长

Yoshimi Endo Greer, Samuel F Gilbert, Brunilde Gril, Rajesh Narwal, Danielle L Peacock Brooks, David A Tice, Patricia S Steeg, Stanley Lipkowitz

ONC201 kills breast cancer cells in vitro by targeting mitochondria

ONC201 通过靶向线粒体在体外杀死乳腺癌细胞

Yoshimi Endo Greer, Natalie Porat-Shliom, Kunio Nagashima, Christina Stuelten, Dan Crooks, Vishal N Koparde, Samuel F Gilbert, Celia Islam, Ashley Ubaldini, Yun Ji, Luca Gattinoni, Ferri Soheilian, Xiantao Wang, Markus Hafner, Jyoti Shetty, Bao Tran, Parthav Jailwala, Maggie Cam, Martin Lang, Donna

Lack of Casein Kinase 1 Delta Promotes Genomic Instability - The Accumulation of DNA Damage and Down-Regulation of Checkpoint Kinase 1

酪蛋白激酶 1 Delta 缺乏会促进基因组不稳定性 - DNA 损伤的积累和检查点激酶 1 的下调

Yoshimi Endo Greer, Bo Gao, Yingzi Yang, Andre Nussenzweig, Jeffrey S Rubin

ONC201: Stressing tumors to death

ONC201:通过压力杀死肿瘤

Endo Greer, Yoshimi; Lipkowitz, Stanley

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis

酪蛋白激酶 1δ 在着丝粒和高尔基体中发挥作用,促进纤毛发生

Yoshimi Endo Greer, Christopher J Westlake, Bo Gao, Kapil Bharti, Yoko Shiba, Charles P Xavier, Gregory J Pazour, Yingzi Yang, Jeffrey S Rubin

Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling

Wnt 诱导的散乱 2 磷酸化对经典和非经典 Wnt 信号传导的功能影响

José M González-Sancho, Yoshimi Endo Greer, Cristina L Abrahams, Yutaka Takigawa, Bolormaa Baljinnyam, Kyung Ho Lee, Kyung S Lee, Jeffrey S Rubin, Anthony M C Brown