日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Plasminogen activator inhibitor 1 promotes aortic aging-like pathophysiology in humans and mice

纤溶酶原激活物抑制剂 1 可促进人类和小鼠的主动脉衰老样病理生理变化

Khoddam, Alireza; Kalousdian, Anthony; Eren, Mesut; Soberanes, Saul; Decker, Andrew; Lux, Elizabeth J; Zywicki, Benjamin W; Dinh, Brian; Boztepe, Bedirhan; Cheema, Baljash S; Cuda, Carla M; Abdala-Valencia, Hiam; Sivakumar, Arun; Miyata, Toshio; Wilsbacher, Lisa D; Vaughan, Douglas E

PAI-1 contributes to homocysteine-induced cellular senescence.

PAI-1 促进同型半胱氨酸诱导的细胞衰老

Sun Tianjiao, Ghosh Asish K, Eren Mesut, Miyata Toshio, Vaughan Douglas E

TGF-β-induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche

TGF-β诱导的细胞内PAI-1负责将造血干细胞保留在干细胞微环境中。

Yahata, Takashi; Ibrahim, Abd Aziz; Muguruma, Yukari; Eren, Mesut; Shaffer, Alexander M; Watanabe, Nobuo; Kaneko, Satoko; Nakabayashi, Tetsuo; Dan, Takashi; Hirayama, Noriaki; Vaughan, Douglas E; Miyata, Toshio; Ando, Kiyoshi

A null mutation in SERPINE1 protects against biological aging in humans

SERPINE1基因的无效突变可保护人类免受生物衰老的影响。

Khan, Sadiya S; Shah, Sanjiv J; Klyachko, Ekaterina; Baldridge, Abigail S; Eren, Mesut; Place, Aaron T; Aviv, Abraham; Puterman, Eli; Lloyd-Jones, Donald M; Heiman, Meadow; Miyata, Toshio; Gupta, Sweta; Shapiro, Amy D; Vaughan, Douglas E

PAI-1 is a critical regulator of FGF23 homeostasis.

PAI-1 是 FGF23 稳态的关键调节因子

Eren Mesut, Place Aaron T, Thomas Paul M, Flevaris Panagiotis, Miyata Toshio, Vaughan Douglas E

Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence

纤溶酶原激活物抑制剂-1是衰老的标志物和介质

Vaughan, Douglas E; Rai, Rahul; Khan, Sadiya S; Eren, Mesut; Ghosh, Asish K

NLRC3 protein inhibits inflammation by disrupting NALP3 inflammasome assembly via competition with the adaptor protein ASC for pro-caspase-1 binding

NLRC3 蛋白通过与衔接蛋白 ASC 竞争 pro-caspase-1 结合来破坏 NALP3 炎症小体的组装,从而抑制炎症

Elif Eren, Mesut Berber, Nesrin Özören

ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model

ApoE 缺乏会加剧半慢性 K/BxN 血清转移诱导的关节炎模型的发展和维持。

Archer, Amy M; Saber, Rana; Rose, Shawn; Shaffer, Alexander; Misharin, Alexander V; Tsai, FuNien; Haines Iii, G Kenneth; Dominguez, Salina; Eren, Mesut; Vaughan, Douglas E; Cuda, Carla M; Perlman, Harris

Role of plasminogen activator inhibitor-1 in senescence and aging

纤溶酶原激活物抑制剂-1在衰老和老化中的作用

Eren, Mesut; Boe, Amanda E; Klyachko, Ekaterina A; Vaughan, Douglas E

A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis

一种新型小鼠模型,可自发性患上关节炎并易患动脉粥样硬化

Rose, Shawn; Eren, Mesut; Murphy, Sheila; Zhang, Heng; Thaxton, Colby Shad; Chowaniec, Jaime; Waters, Emily A; Meade, Thomas J; Vaughan, Douglas E; Perlman, Harris