日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Characterizing the impact of MLL fusion variants and fusion partners on leukemia plasticity using a human CRISPR-engineered MLL-rearranged leukemia model

利用人源 CRISPR 基因编辑的 MLL 重排白血病模型,研究 MLL 融合变体及其融合伴侣对白血病可塑性的影响

Radszuweit, Pia; Fitzel, Rahel; Bruestl, Sarah; Hentrich, Thomas; Korkmaz, Fulya; Mankel, Barbara; González-Menéndez, Irene; Rudat, Saskia; Marschalek, Rolf; Erkner, Estelle; Keppeler, Hildegard; Schairer, Rebekka; Luib, Luise; Mezger, Markus; Quintanilla-Martinez, Leticia; Schulze-Hentrich, Julia; Lengerke, Claudia; Schneidawind, Dominik; Schneidawind, Corina

Protocol for CRISPR-Cas9-mediated induction of KMT2A rearrangements in cell line and umbilical cord blood hematopoietic stem and progenitor cells

利用 CRISPR-Cas9 介导的 KMT2A 重排诱导细胞系和脐带血造血干细胞及祖细胞的实验方案

Tamara Benz ,Patrizia Larghero ,Claus Meyer ,Marcel Müller ,Dörthe Brüggmann ,Anna-Elisabeth Hentrich ,Frank Louwen ,Estelle Erkner ,Rahel Fitzel ,Corina Schneidawind ,Rolf Marschalek

The RORɣ/SREBP2 pathway is a master regulator of cholesterol metabolism and serves as potential therapeutic target in t(4;11) leukemia

RORɣ/SREBP2 通路是胆固醇代谢的主要调节器,可作为 t(4;11) 白血病的潜在治疗靶点

Estelle Erkner, Thomas Hentrich, Rebekka Schairer, Rahel Fitzel, Kathy-Ann Secker-Grob, Johan Jeong, Hildegard Keppeler, Fulya Korkmaz, Julia M Schulze-Hentrich, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind

Treatment response of advanced HNSCC towards immune checkpoint inhibition is associated with an activated effector memory T cell phenotype

晚期头颈部鳞状细胞癌对免疫检查点抑制剂的治疗反应与活化的效应记忆T细胞表型相关

Schumacher, Max; Beer, Sina; Moraes Ribeiro, Emmanuelle; Korkmaz, Fulya; Keppeler, Hildegard; Fitzel, Rahel; Erkner, Estelle; Radszuweit, Pia; Lengerke, Claudia; Schneidawind, Corina; Hoefert, Sebastian; Mauz, Paul Stefan; Schneidawind, Dominik

Uncovering NOTCH1 as a Promising Target in the Treatment of MLL-Rearranged Leukemia

发现 NOTCH1 是治疗 MLL 重排白血病的一个有前景的靶点

Jacqueline Fischer ,Estelle Erkner ,Rahel Fitzel ,Pia Radszuweit ,Hildegard Keppeler ,Fulya Korkmaz ,Giovanni Roti ,Claudia Lengerke ,Dominik Schneidawind ,Corina Schneidawind

Targeting MYC in combination with epigenetic regulators induces synergistic anti-leukemic effects in MLLr leukemia and simultaneously improves immunity

以 MYC 为靶点,结合表观遗传调节剂,可在 MLLr 白血病中产生协同抗白血病作用,同时提高免疫力

Rahel Fitzel, Kathy-Ann Secker-Grob, Hildegard Keppeler, Fulya Korkmaz, Rebekka Schairer, Estelle Erkner, Dominik Schneidawind, Claudia Lengerke, Thomas Hentrich, Julia M Schulze-Hentrich, Corina Schneidawind

Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes

vaspin N 端的裂解会释放出细胞穿透肽,影响脂肪生成的早期阶段并抑制成熟脂肪细胞中的脂肪分解

Catherine A Tindall, Estelle Erkner, Jan Stichel, Annette G Beck-Sickinger, Anne Hoffmann, Juliane Weiner, John T Heiker

Effects of Oral Exposure Duration and Gastric Energy Content on Appetite Ratings and Energy Intake in Lean Men

口服暴露时间和胃能量含量对瘦男性食欲评分和能量摄入的影响

Wijlens, Anne G M; de Graaf, Cees; Erkner, Alfrun; Mars, Monica

The C-terminal domain of armadillo binds to hypophosphorylated teashirt to modulate wingless signalling in Drosophila

armadillo 的 C 端结构域与低磷酸化的 teashirt 结合,从而调节果蝇中的 wingless 信号传导。

Gallet, A; Angelats, C; Erkner, A; Charroux, B; Fasano, L; Kerridge, S