日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hampered AMPK-ULK1 cascade in Alzheimer's disease (AD) instigates mitochondria dysfunctions and AD-related alterations which are alleviated by metformin.

阿尔茨海默病 (AD) 中 AMPK-ULK1 级联受阻,引发线粒体功能障碍和 AD 相关改变,而二甲双胍可以缓解这些改变

Mary Arnaud, Barale Samantha, Eysert Fanny, Valverde Audrey, Lacas-Gervais Sandra, Bauer Charlotte, Eddarkaoui Sabiha, Buée Luc, Buée-Scherrer Valérie, Checler Frédéric, Chami Mounia

The amyloid precursor protein and its derived fragments concomitantly contribute to the alterations of mitochondrial transport machinery in Alzheimer's disease

淀粉样蛋白前体及其衍生片段同时导致阿尔茨海默病中线粒体运输机制的改变

Loan Vaillant-Beuchot, Fanny Eysert, Blandine Duval, Paula Fernanda Kinoshita, Raphaëlle Pardossi-Piquard, Charlotte Bauer, Sabiha Eddarkaoui, Luc Buée, Frédéric Checler, Mounia Chami

Mitochondrial alterations in fibroblasts from sporadic Alzheimer's disease (AD) patients correlate with AD-related clinical hallmarks

散发性阿尔茨海默病(AD)患者成纤维细胞线粒体改变与AD相关临床特征相关

Fanny Eysert ,Paula-Fernanda Kinoshita ,Julien Lagarde ,Sandra Lacas-Gervais ,Laura Xicota ,Guillaume Dorothée ,Michel Bottlaender ,Frédéric Checler ,Marie-Claude Potier ,Marie Sarazin ,Mounia Chami

Mitophagy in Alzheimer's disease: Molecular defects and therapeutic approaches

线粒体自噬在阿尔茨海默病中的作用:分子缺陷和治疗方法

Mary, Arnaud; Eysert, Fanny; Checler, Frédéric; Chami, Mounia

Modifications of the endosomal compartment in fibroblasts from sporadic Alzheimer's disease patients are associated with cognitive impairment

散发性阿尔茨海默病患者成纤维细胞内体区室的改变与认知障碍有关

Laura Xicota, Julien Lagarde, Fanny Eysert, Benjamin Grenier-Boley, Isabelle Rivals, Alexandra Botté, Sylvie Forlani, Sophie Landron, Clément Gautier, Cecilia Gabriel, Michel Bottlaender, Jean-Charles Lambert, Mounia Chami, Marie Sarazin, Marie-Claude Potier

Correction to: Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner

更正:阿尔茨海默病遗传风险因子FERMT2(Kindlin-2)以APP依赖的方式控制轴突生长和突触可塑性

Eysert, Fanny; Coulon, Audrey; Boscher, Emmanuelle; Vreulx, Anaїs-Camille; Flaig, Amandine; Mendes, Tiago; Hughes, Sandrine; Grenier-Boley, Benjamin; Hanoulle, Xavier; Demiautte, Florie; Bauer, Charlotte; Marttinen, Mikael; Takalo, Mari; Amouyel, Philippe; Desai, Shruti; Pike, Ian; Hiltunen, Mikko; Chécler, Frédéric; Farinelli, Mélissa; Delay, Charlotte; Malmanche, Nicolas; Hébert, Sébastien S; Dumont, Julie; Kilinc, Devrim; Lambert, Jean-Charles; Chapuis, Julien

Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner

阿尔茨海默氏症遗传风险因子 FERMT2 (Kindlin-2) 以 APP 依赖的方式控制轴突生长和突触可塑性

Fanny Eysert, Audrey Coulon, Emmanuelle Boscher, Anaїs-Camille Vreulx, Amandine Flaig, Tiago Mendes, Sandrine Hughes, Benjamin Grenier-Boley, Xavier Hanoulle, Florie Demiautte, Charlotte Bauer, Mikael Marttinen, Mari Takalo, Philippe Amouyel, Shruti Desai, Ian Pike, Mikko Hiltunen, Frédéric Chécler,

Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains

淀粉样蛋白前体 C 端片段的积累会引发阿尔茨海默病模型和人类大脑中的线粒体结构、功能和线粒体自噬缺陷

Loan Vaillant-Beuchot #, Arnaud Mary #, Raphaëlle Pardossi-Piquard, Alexandre Bourgeois, Inger Lauritzen, Fanny Eysert, Paula Fernanda Kinoshita, Julie Cazareth, Céline Badot, Konstantina Fragaki, Renaud Bussiere, Cécile Martin, Rosanna Mary, Charlotte Bauer, Sophie Pagnotta, Véronique Paquis-Fluckl

Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and its impact on neuron biology

弓形虫对原发性脑细胞的感染揭示了寄生虫分化的程度和动态及其对神经元生物学的影响

Mouveaux, Thomas; Roger, Emmanuel; Gueye, Alioune; Eysert, Fanny; Huot, Ludovic; Grenier-Boley, Benjamin; Lambert, Jean-Charles; Gissot, Mathieu

Pyk2 overexpression in postsynaptic neurons blocks amyloid β1-42-induced synaptotoxicity in microfluidic co-cultures

突触后神经元中的 Pyk2 过表达可阻断微流体共培养中淀粉样蛋白 β1-42 诱导的突触毒性

Devrim Kilinc, Anaïs-Camille Vreulx, Tiago Mendes, Amandine Flaig, Diego Marques-Coelho, Maxime Verschoore, Florie Demiautte, Philippe Amouyel; Neuro-CEB Brain Bank; Fanny Eysert, Pierre Dourlen, Julien Chapuis, Marcos R Costa, Nicolas Malmanche, Frédéric Checler, Jean-Charles Lambert