BRAF inhibition increases TGFβ2 production and stimulates metastasis in mice with endogenous BRAF(V600E)-induced hepatocellular carcinoma
BRAF抑制剂可增加TGFβ2的产生,并刺激内源性BRAF(V600E)诱导的肝细胞癌小鼠的转移。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2503044122
Cisowski, Jaroslaw; El Zowalaty, Ahmed Ezat; Sayin, Sama I; Czarnota, Piotr; Gromowski, Tomasz; Eklund, Ella A; Kashif, Muhammad; Patel, Angana A H; Molinaro, Antonio; Lindahl, Per; Wiel, Clotilde; Sayin, Volkan I; Bergo, Martin O