Fa-jun Nan相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84

中链脂肪酸感应受体 GPR84 的配体识别和激活的结构洞察

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-38985-6

Heng Liu #, Qing Zhang #, Xinheng He #, Mengting Jiang, Siwei Wang, Xiaoci Yan, Xi Cheng, Yang Liu, Fa-Jun Nan, H Eric Xu, Xin Xie, Wanchao Yin

发表日期：2023

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GPR84 regulates pulmonary inflammation by modulating neutrophil functions

GPR84通过调节中性粒细胞功能来调控肺部炎症。

期刊:Acta Pharmacologica Sinica

影响因子:6.9

doi:10.1038/s41401-023-01080-z

Si-Wei Wang # ，Qing Zhang # ，Dan Lu ，You-Chen Fang ，Xiao-Ci Yan ，Jing Chen ，Zhi-Kan Xia ，Qian-Ting Yuan ，Lin-Hai Chen ，Yang-Ming Zhang ，Fa-Jun Nan ，Xin Xie

中性粒细胞

细胞生物学

发表日期：2023

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Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma

新型组蛋白去乙酰化酶抑制剂 bisthianostat 治疗复发或难治性多发性骨髓瘤的药效学、药代动力学及 1a 期研究

期刊:Acta Pharmacologica Sinica

影响因子:6.9

doi:10.1038/s41401-021-00728-y

Yu-Bo Zhou #, Yang-Ming Zhang #, Hong-Hui Huang #, Li-Jing Shen, Xiao-Feng Han, Xiao-Bei Hu, Song-da Yu, An-Hui Gao, Li Sheng, Ming-Bo Su, Xiao-Li Wei, Yue Zhang, Yi-Fan Zhang, Zhi-Wei Gao, Xiao-Yan Chen, Fa-Jun Nan, Jia Li, Jian Hou1

发表日期：2022

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GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages

GPR84信号通过增强巨噬细胞中NLRP3炎症小体的活化来促进肠粘膜炎症

期刊:Acta Pharmacologica Sinica

影响因子:6.9

doi:10.1038/s41401-021-00825-y

Qing Zhang #, Lin-Hai Chen #, Hui Yang #, You-Chen Fang, Si-Wei Wang, Min Wang, Qian-Ting Yuan, Wei Wu, Yang-Ming Zhang, Zhan-Ju Liu, Fa-Jun Nan, Xin Xie2

细胞生物学

发表日期：2022

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Pyrazolone derivative C29 protects against HFD-induced obesity in mice via activation of AMPK in adipose tissue

吡唑酮衍生物 C29 通过激活脂肪组织中的 AMPK 预防小鼠因高脂饮食引起的肥胖

期刊:Acta Pharmacologica Sinica

影响因子:6.9

doi:10.1038/s41401-020-00524-0

Bo-Han Li, Mei Zhang, Ya-Nan Duan, Lin Shuai, Hao-Wen Jiang, Jia Li, Fa-Jun Nan, Jing-Ya Li

发表日期：2021

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AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models

AMPK 激活剂 C24 可抑制肝脏脂肪生成并改善 HFHC 饮食诱发的动物模型中的血脂异常

期刊:Acta Pharmacologica Sinica

影响因子:6.9

doi:10.1038/s41401-020-0472-9

Shui-Mei Sun #, Zhi-Fu Xie #, Yang-Ming Zhang #, Xin-Wen Zhang, Chen-Dong Zhou, Jian-Peng Yin, Yan-Yan Yu, Shi-Chao Cui, Hao-Wen Jiang, Teng-Teng Li, Jia Li, Fa-Jun Nan, Jing-Ya Li

发表日期：2021

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Berberine derivatives with a long alkyl chain branched by hydroxyl group and methoxycarbonyl group at 9-position show improved anti-proliferation activity and membrane permeability in A549 cells

9位上含有羟基和甲氧羰基的长烷基链小檗碱衍生物在A549细胞中表现出增强的抗增殖活性和膜通透性

期刊:Acta Pharmacologica Sinica

影响因子:6.9

doi:10.1038/s41401-019-0346-1

Yi Liu #, Ke-Xin Zhu #, Lei Cao, Zhi-Fu Xie, Min Gu, Wei Lü, Jing-Ya Li, Fa-Jun Nan

细胞生物学

发表日期：2020

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Sulfuretin protects hepatic cells through regulation of ROS levels and autophagic flux

硫脲通过调节 ROS 水平和自噬通量保护肝细胞

期刊:Acta Pharmacologica Sinica

影响因子:6.9

doi:10.1038/s41401-018-0193-5

Yu-Ting Lu #, Yu-Feng Xiao #, Yu-Feng Li, Jia Li, Fa-Jun Nan, Jing-Ya Li

细胞生物学

发表日期：2019

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Isothiafludine, a novel non-nucleoside compound, inhibits hepatitis B virus replication through blocking pregenomic RNA encapsidation

异噻氟啶是一种新型非核苷化合物，通过阻断前基因组 RNA 衣壳化来抑制乙型肝炎病毒复制

期刊:Acta Pharmacologica Sinica

影响因子:6.9

doi:10.1038/aps.2013.175

Li Yang, Li-ping Shi, Hai-jun Chen, Xian-kun Tong, Gui-feng Wang, Yang-ming Zhang, Wen-long Wang, Chun-lan Feng, Pei-lan He, Feng-hua Zhu, You-hua Hao, Bao-ju Wang, Dong-liang Yang, Wei Tang, Fa-jun Nan, Jian-ping Zuo

发表日期：2014

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Highly lipophilic 3-epi-betulinic acid derivatives as potent and selective TGR5 agonists with improved cellular efficacy

高度亲脂性的 3-表桦木酸衍生物作为有效且选择性的 TGR5 激动剂，具有改善细胞功效

期刊:Acta Pharmacologica Sinica

影响因子:6.9

doi:10.1038/aps.2014.97

Xiao-yin Wang, Shu-yong Zhang, Jing Li, Hua-nan Liu, Xin Xie, Fa-jun Nan

细胞生物学

发表日期：2014

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