日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lentiviral-mediated knock-down of GD3 synthase protects against MPTP-induced motor deficits and neurodegeneration.

慢病毒介导的GD3合成酶敲低可防止MPTP诱导的运动障碍和神经退行性变

Dhanushkodi Anandh, Xue Yi, Roguski Emily E, Ding Yun, Matta Shannon G, Heck Detlef, Fan Guo-Huang, McDonald Michael P

Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes

肌萎缩侧索硬化症单核细胞基因表达表型的特征分析

Zhao, Weihua; Beers, David R; Hooten, Kristopher G; Sieglaff, Douglas H; Zhang, Aijun; Kalyana-Sundaram, Shanker; Traini, Christopher M; Halsey, Wendy S; Hughes, Ashley M; Sathe, Ganesh M; Livi, George P; Fan, Guo-Huang; Appel, Stanley H

Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation

USP14 对 CXCR4 的去泛素化作用对于 CXCL12 诱导的 CXCR4 降解和趋化作用至关重要,但对 ERK 激活并非关键因素。

Mines, Marjelo A; Goodwin, J Shawn; Limbird, Lee E; Cui, Fei-Fei; Fan, Guo-Huang

Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model

视黄酸可减轻β-淀粉样蛋白沉积,并改善阿尔茨海默病转基因小鼠模型的记忆缺陷。

Ding, Yun; Qiao, Aimin; Wang, Ziqing; Goodwin, J Shawn; Lee, Eun-Sook; Block, Michelle L; Allsbrook, Matthew; McDonald, Michael P; Fan, Guo-Huang

Plectin regulates the signaling and trafficking of the HIV-1 co-receptor CXCR4 and plays a role in HIV-1 infection

Plectin 调节 HIV-1 辅助受体 CXCR4 的信号传导和转运,并在 HIV-1 感染中发挥作用。

Ding, Yun; Zhang, Li; Goodwin, J Shawn; Wang, Ziqing; Liu, Bingdong; Zhang, Jingwu; Fan, Guo-Huang

Chemokine receptor internalization and intracellular trafficking

趋化因子受体内化和细胞内转运

Neel, Nicole F; Schutyser, Evemie; Sai, Jiqing; Fan, Guo-Huang; Richmond, Ann

The C-terminal domain LLKIL motif of CXCR2 is required for ligand-mediated polarization of early signals during chemotaxis

CXCR2 的 C 端结构域 LLKIL 基序是趋化过程中配体介导的早期信号极化所必需的

Sai, Jiqing; Fan, Guo-Huang; Wang, Dingzhi; Richmond, Ann

Rab11-family interacting protein 2 and myosin Vb are required for CXCR2 recycling and receptor-mediated chemotaxis

Rab11家族相互作用蛋白2和肌球蛋白Vb是CXCR2再循环和受体介导的趋化作用所必需的。

Fan, Guo-Huang; Lapierre, Lynne A; Goldenring, James R; Sai, Jiqing; Richmond, Ann