Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer
揭示重连的IAP-JAK调控轴是LKB1突变型肺癌的免疫依赖性脆弱性
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-57297-5
Changfa Shu ,Jianfeng Li ,Jin Rui ,Dacheng Fan ,Qiankun Niu ,Ruiyang Bai ,Danielle Cicka ,Sean Doyle ,Alafate Wahafu ,Xi Zheng ,Yuhong Du ,Andrey A Ivanov ,Deon B Doxie ,Kavita M Dhodapkar ,Jennifer Carlisle ,Taofeek Owonikoko ,Gabriel Sica ,Yuan Liu ,Suresh Ramalingam ,Madhav V Dhodapkar ,Wei Zhou ,Xiulei Mo ,Haian Fu
免疫/内分泌
信号转导
肿瘤免疫
肺癌
JAK/STAT
肿瘤
