Histone lactylation leads to perioperative neurocognitive disorders by promoting the expression of Ralbp1 and inducing excessive mitochondrial fission in hippocampal neurons
组蛋白乳酸化通过促进Ralbp1的表达和诱导海马神经元中线粒体过度分裂,导致围手术期神经认知障碍。
期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-026-06095-3
Meng, Fanbing; Cao, Silu; Wu, Weifeng; Zhang, Meixian; Jing, Qi; Xie, Zheng; Sun, Xiaoxiao; Song, Jian; Fei, Miaomiao; Chen, Qian; Gao, Xiaofei; Li, Cheng