日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Histone H3E50K remodels chromatin to confer oncogenic activity and support an EMT phenotype

组蛋白 H3E50K 重塑染色质,赋予致癌活性并支持 EMT 表型

Kirti Sad, Dorelle V Fawwal, Celina Y Jones, Emily J Hill, Katie T Skinner, Miranda L Adams, Severin Lustenberger, Richard S Lee, Sandhya V Lohano, Satvik R Elayavalli, Jonathan Farhi, Christina C Mehta, Laramie D Lemon, Milo B Fasken, Andrew L Hong, Steven A Sloan, Anita H Corbett, Jennifer M Spang

Humanized Saccharomyces cerevisiae provides a facile and effective tool to identify damaging human variants that cause exosomopathies.

人源化酿酒酵母为识别导致外泌体病的有害人类变异体提供了一种简便有效的工具

Ahammed Khondakar Sayef, Fasken Milo B, Corbett Anita H, van Hoof Ambro

A biallelic variant of the RNA exosome gene, EXOSC4, associated with neurodevelopmental defects impairs RNA exosome function and translation

与神经发育缺陷相关的 RNA 外泌体基因的双等位基因变体 EXOSC4 会损害 RNA 外泌体的功能和翻译

Milo B Fasken, Sara W Leung, Lauryn A Cureton, Maha Al-Awadi, Adila Al-Kindy, Ambro van Hoof, Sohail Khoshnevis, Homa Ghalei, Almundher Al-Maawali, Anita H Corbett

The Drosophila Nab2 RNA binding protein inhibits m6A methylation and male-specific splicing of Sex lethal transcript in female neuronal tissue

果蝇 Nab2 RNA 结合蛋白抑制雌性神经元组织中 m6A 甲基化和性致死转录本的雄性特异性剪接

Binta Jalloh #, Carly L Lancaster #, J Christopher Rounds #, Brianna E Brown #, Sara W Leung, Ayan Banerjee, Derrick J Morton, Rick S Bienkowski, Milo B Fasken, Isaac J Kremsky, Matthew Tegowski, Kate Meyer, Anita Corbett, Ken Moberg

In vivo characterization of the critical interaction between the RNA exosome and the essential RNA helicase Mtr4 in Saccharomyces cerevisiae

酿酒酵母中RNA外泌体与必需RNA解旋酶Mtr4之间关键相互作用的体内表征

Sterrett, Maria C; Farchi, Daniela; Strassler, Sarah E; Boise, Lawrence H; Fasken, Milo B; Corbett, Anita H

A Saccharomyces cerevisiae model and screen to define the functional consequences of oncogenic histone missense mutations

酿酒酵母模型和筛选以确定致癌组蛋白错义突变的功能后果

Laramie D Lemon, Sneha Kannan, Kim Wai Mo, Miranda Adams, Haley G Choi, Alexander O D Gulka, Elise S Withers, Hasset T Nurelegne, Valeria Gomez, Reina E Ambrocio, Rhea Tumminkatti, Richard S Lee, Morris Wan, Milo B Fasken, Jennifer M Spangle, Anita H Corbett

A budding yeast model for human disease mutations in the EXOSC2 cap subunit of the RNA exosome complex

利用出芽酵母模型研究RNA外泌体复合物EXOSC2帽亚基的人类疾病突变

Sterrett, Maria C; Enyenihi, Liz; Leung, Sara W; Hess, Laurie; Strassler, Sarah E; Farchi, Daniela; Lee, Richard S; Withers, Elise S; Kremsky, Isaac; Baker, Richard E; Basrai, Munira A; van Hoof, Ambro; Fasken, Milo B; Corbett, Anita H

A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons

果蝇脑桥小脑发育不全模型揭示了RNA外泌体在神经元中的关键作用

Morton, Derrick J; Jalloh, Binta; Kim, Lily; Kremsky, Isaac; Nair, Rishi J; Nguyen, Khuong B; Rounds, J Christopher; Sterrett, Maria C; Brown, Brianna; Le, Thalia; Karkare, Maya C; McGaughey, Kathryn D; Sheng, Shaoyi; Leung, Sara W; Fasken, Milo B; Moberg, Kenneth H; Corbett, Anita H

Dissecting the roles of Cse1 and Nup2 in classical NLS-cargo release in vivo

解析Cse1和Nup2在体内经典NLS-货物释放中的作用

Lange, Allison; Fasken, Milo B; Stewart, Murray; Corbett, Anita H

Structure-function relationships in the Nab2 polyadenosine-RNA binding Zn finger protein family

Nab2聚腺苷酸-RNA结合锌指蛋白家族的结构-功能关系

Fasken, Milo B; Corbett, Anita H; Stewart, Murray