日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A unique inhibitor conformation selectively targets the DNA polymerase PolC of Gram-positive priority pathogens

一种独特的抑制剂构象选择性地靶向革兰氏阳性优先病原体的DNA聚合酶PolC

Urem, Mia; Friggen, Annemieke H; Musch, Nina; Silverman, Michael H; Swain, Christopher J; Barbachyn, Michael R; Mortin, Lawrence I; Yu, Xiang; DeLuccia, Robert J; Lamers, Meindert H; Smits, Wiep Klaas

New insights into the type A glycan modification of Clostridioides difficile flagellar protein flagellin C by phosphoproteomics analysis

通过磷酸化蛋白质组学分析对艰难梭菌鞭毛蛋白鞭毛蛋白 C 的 A 型聚糖修饰有了新的认识

Paul J Hensbergen, Arnoud H de Ru, Annemieke H Friggen, Jeroen Corver, Wiep Klaas Smits, Peter A van Veelen

Clostridioides difficile Phosphoproteomics Shows an Expansion of Phosphorylated Proteins in Stationary Growth Phase

艰难梭菌磷酸化蛋白质组学表明,静止生长期中磷酸化蛋白质扩增

Wiep Klaas Smits, Yassene Mohammed, Arnoud H de Ru, Valentina Cordo', Annemieke H Friggen, Peter A van Veelen, Paul J Hensbergen

Identification of the Unwinding Region in the Clostridioides difficile Chromosomal Origin of Replication

艰难梭菌染色体复制起点解旋区的鉴定

Oliveira Paiva, Ana M; van Eijk, Erika; Friggen, Annemieke H; Weigel, Christoph; Smits, Wiep Klaas

The C-Terminal Domain of Clostridioides difficile TcdC Is Exposed on the Bacterial Cell Surface

艰难梭菌 TcdC 的 C 端结构域暴露在细菌细胞表面

Ana M Oliveira Paiva, Leen de Jong, Annemieke H Friggen, Wiep Klaas Smits, Jeroen Corver

Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile

引物酶是解旋酶活性所必需的,而解旋酶会改变肠道致病菌艰难梭菌中引物酶的特异性。

van Eijk, Erika; Paschalis, Vasileios; Green, Matthew; Friggen, Annemieke H; Larson, Marilynn A; Spriggs, Keith; Briggs, Geoffrey S; Soultanas, Panos; Smits, Wiep Klaas

Clonal analysis of the T-cell response to in vivo expressed Mycobacterium tuberculosis protein Rv2034, using a CD154 expression based T-cell cloning method

利用基于CD154表达的T细胞克隆方法,对体内表达的结核分枝杆菌蛋白Rv2034的T细胞反应进行克隆分析

Commandeur, Susanna; Coppola, Mariateresa; Dijkman, Karin; Friggen, Annemieke H; van Meijgaarden, Krista E; van den Eeden, Susan J F; Wilson, Louis; van der Ploeg-van Schip, Jolien J; Franken, Kees L M C; Geluk, Annemieke; Ottenhoff, Tom H M

Analysis of immune responses against a wide range of Mycobacterium tuberculosis antigens in patients with active pulmonary tuberculosis.

分析活动性肺结核患者对多种结核分枝杆菌抗原的免疫反应

Kassa Desta, Ran Leonie, Geberemeskel Wudneh, Tebeje Mekashaw, Alemu Amelewerk, Selase Alemayehu, Tegbaru Belete, Franken Kees L M C, Friggen Annemieke H, van Meijgaarden Krista E, Ottenhoff Tom H M, Wolday Dawit, Messele Tsehaynesh, van Baarle Debbie

Identification of human T-cell responses to Mycobacterium tuberculosis resuscitation-promoting factors in long-term latently infected individuals

鉴定长期潜伏感染者体内针对结核分枝杆菌复苏促进因子的T细胞反应

Commandeur, Susanna; van Meijgaarden, Krista E; Lin, May Young; Franken, Kees L M C; Friggen, Annemieke H; Drijfhout, Jan Wouter; Oftung, Fredrik; Korsvold, Gro Ellen; Geluk, Annemieke; Ottenhoff, Tom H M

Cross-reactive immunity to Mycobacterium tuberculosis DosR regulon-encoded antigens in individuals infected with environmental, nontuberculous mycobacteria

环境非结核分枝杆菌感染者对结核分枝杆菌DosR调控子编码抗原的交叉反应性免疫

Lin, May Young; Reddy, T B K; Arend, Sandra M; Friggen, Annemieke H; Franken, Kees L M C; van Meijgaarden, Krista E; Verduyn, Marleen J C; Schoolnik, Gary K; Klein, Michel R; Ottenhoff, Tom H M