日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Context-dependent variability of HIF heterodimers influences interactions with macromolecular and small molecule partners

HIF异二聚体的环境依赖性变异会影响其与大分子和小分子伴侣的相互作用。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2514042123
Closson, Joseph D; Xu, Xingjian; Zhang, Meiling; Tiyani, Tarsisius T; Marcelino, Leandro Pimentel; Isiorho, Eta A; Nagati, Jason S; Garcia, Joseph A; Gardner, Kevin H
发表日期：2026
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Small Molecule Regulation of CLOCK:BMAL1 DNA Binding Activity

小分子调控CLOCK:BMAL1 DNA结合活性

期刊:
影响因子:
doi:10.64898/2026.04.13.718289
Sharma, Diksha; Boral, Soumendu; West, Ethen; Kressman, McClain; Franco, Irene; Tripathi, Sarvind; Lee, Hsiau-Wei; Amezcua, Carlos A; Favaro, Denize C; Gardner, Kevin H; Partch, Carrie L
CLOCK
信号转导
BMAL1
发表日期：2026
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Structural Basis of a Novel Heme Binding Bacterial One-Component Switch

一种新型血红素结合细菌单组分开关的结构基础

期刊:
影响因子:
doi:10.64898/2026.03.15.711900
Siclari, James J; Forson, Malvin; Roeder, Cullen; Isiorho, Eta A; Favaro, Denize C; Abzalimov, Rinat R; Gisselbrecht, Stephen S; Follmer, Alec H; Bulyk, Martha L; Gardner, Kevin H
微生物学
发表日期：2026
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CONTEXT-DEPENDENT VARIABILITY OF HIF HETERODIMERS INFLUENCES INTERACTIONS WITH MACROMOLECULAR AND SMALL MOLECULE PARTNERS

HIF异二聚体的背景依赖性变异影响其与大分子和小分子伴侣的相互作用

期刊:
影响因子:
doi:10.1101/2025.05.29.656908
Closson, Joseph D; Xu, Xingjian; Zhang, Meiling; Tiyani, Tarsisius T; Marcelino, Leandro Pimentel; Isiorho, Eta A; Nagati, Jason S; Garcia, Joseph A; Gardner, Kevin H
发表日期：2025
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Intramolecular competition generates pulsatory protein activity shaped by light, temperature, and evolution

分子内竞争产生脉冲式蛋白质活性，这种活性受光照、温度和进化的影响。

期刊:
影响因子:
doi:10.1101/2025.04.08.647774
Huang, Zikang Dennis; Forson, Malvin; Benman, William; Gardner, Kevin H; Bugaj, Lukasz J
发表日期：2025
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Use of High Pressure NMR Spectroscopy to Rapidly Identify Proteins with Internal Ligand-Binding Voids

利用高压核磁共振波谱快速鉴定具有内部配体结合空隙的蛋白质

期刊:
影响因子:
doi:10.1101/2020.08.25.267195
Gagné, Donald; Azad, Roksana; Aramini, James M; Xu, Xingjian; Isiorho, Eta A; Edupuganti, Uthama R; Williams, Justin P; Marcelino, Leandro Pimentel; Johnson, Bruce A; Akasaka, Kazuyuki; Gardner, Kevin H
发表日期：2025
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Hydraulic Activation of the AsLOV2 Photoreceptor

AsLOV2光感受器的液压激活

期刊:
影响因子:
doi:10.1101/2025.06.19.660617
Maity, Shiny; Sheppard, Jackson; Russell, Hannah; Han, Chung-Ta; Epstein, Leah; Johnson, Bruce A; Price, Brad; Han, Ruixian; Potnuru, Lokeswara Rao; Cui, Jinlei; Sherwin, Mark S; Shea, Joan-Emma; Lovett, Janet E; Gardner, Kevin H; Han, Songi
发表日期：2025
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Gating residues govern ligand unbinding kinetics from the buried cavity in HIF-2α PAS-B

门控残基控制配体从 HIF-2α PAS-B 埋藏腔中解离的动力学

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.5198
Silvestrini, Marion L; Solazzo, Riccardo; Boral, Soumendu; Cocco, Melanie J; Closson, Joseph D; Masetti, Matteo; Gardner, Kevin H; Chong, Lillian T
发表日期：2024
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Signal-regulated Unmasking of Nuclear Localization Motif in the PAS Domain Regulates the Nuclear Translocation of PASK.

PAS结构域中核定位基序的信号调控揭示调节PASK的核转位

期刊:Journal of Molecular Biology
影响因子:4.5
doi:10.1016/j.jmb.2023.168433
Xiao Michael, Dhungel Sajina, Azad Roksana, Favaro Denize C, Rajesh Rajaian Pushpabai, Gardner Kevin H, Kikani Chintan K
信号转导
发表日期：2024
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Identification of small-molecule ligand-binding sites on and in the ARNT PAS-B domain

鉴定ARNT PAS-B结构域上及内部的小分子配体结合位点

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2024.107606
Xu, Xingjian; Closson, Joseph D; Marcelino, Leandro Pimentel; Favaro, Denize C; Silvestrini, Marion L; Solazzo, Riccardo; Chong, Lillian T; Gardner, Kevin H
ARNT
发表日期：2024
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