日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Highly specific intracellular ubiquitination of a small molecule

小分子的高度特异性细胞内泛素化

Weicheng Li, Enrique M Garcia-Rivera, Dylan C Mitchell, Joel M Chick, Micah Maetani, John M Knapp, Geoffrey M Matthews, Ryosuke Shirasaki, Ricardo de Matos Simoes, Vasanthi Viswanathan, John L Pulice, Matthew G Rees, Jennifer A Roth, Steven P Gygi, Constantine S Mitsiades, Cigall Kadoch, Stuart L Sc

Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

基因组规模的功能基因组学可识别出对多发性骨髓瘤细胞比其他肿瘤更关键的基因

Ricardo de Matos Simoes #, Ryosuke Shirasaki #, Sondra L Downey-Kopyscinski #, Geoffrey M Matthews #, Benjamin G Barwick #, Vikas A Gupta, Daphné Dupéré-Richer, Shizuka Yamano, Yiguo Hu, Michal Sheffer, Eugen Dhimolea, Olga Dashevsky, Sara Gandolfi, Kazuya Ishiguro, Robin M Meyers, Jordan G Bryan, N

Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins

功能基因组学识别出介导对不同类别异双功能癌蛋白降解剂产生抗性的独特和重叠基因

Ryosuke Shirasaki, Geoffrey M Matthews, Sara Gandolfi, Ricardo de Matos Simoes, Dennis L Buckley, Joseline Raja Vora, Quinlan L Sievers, Johanna B Brüggenthies, Olga Dashevsky, Haley Poarch, Huihui Tang, Megan A Bariteau, Michal Sheffer, Yiguo Hu, Sondra L Downey-Kopyscinski, Paul J Hengeveld, Brian

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene

Eμ-Myc 小鼠淋巴瘤的基因组表征表明 Bcor 是一种 Myc 协同肿瘤抑制基因

Marcus Lefebure, Richard W Tothill, Elizabeth Kruse, Edwin D Hawkins, Jake Shortt, Geoffrey M Matthews, Gareth P Gregory, Benjamin P Martin, Madison J Kelly, Izabela Todorovski, Maria A Doyle, Richard Lupat, Jason Li, Jan Schroeder, Meaghan Wall, Stuart Craig, Gretchen Poortinga, Don Cameron, Megan

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies

小鼠淋巴系统和骨髓恶性肿瘤中 HDAC 依赖性的功能遗传学解析

Geoffrey M Matthews, Parinaz Mehdipour, Leonie A Cluse, Katrina J Falkenberg, Eric Wang, Mareike Roth, Fabio Santoro, Eva Vidacs, Kym Stanley, Colin M House, James R Rusche, Christopher R Vakoc, Johannes Zuber, Saverio Minucci, Ricky W Johnstone

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance

Hdac1 的双重作用:肿瘤发生中的抑癌基因,肿瘤维持中的致癌基因

Fabio Santoro, Oronza A Botrugno, Roberto Dal Zuffo, Isabella Pallavicini, Geoffrey M Matthews, Leonie Cluse, Iros Barozzi, Silvia Senese, Lorenzo Fornasari, Simona Moretti, Lucia Altucci, Pier Giuseppe Pelicci, Susanna Chiocca, Ricky W Johnstone, Saverio Minucci