Optimized chemical structure extends silencing duration of therapeutic siRNAs in dividing cancer and immune cells
优化的化学结构延长了治疗性siRNA在分裂的癌细胞和免疫细胞中的沉默持续时间。
期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2025.08.017
Kremer, Anastasia; Ryaykenen, Tatyana; Segarra-Visent, Xavier; Sauer, Melanie; Breuer, Leon; Wu, Yiying; Tang, Qi; Cooper, David A; Echeverria, Dimas; Philouze, Clothilde; Bayon, Emilie; Georgess, Dan; Haraszti, Reka A